β-乙氧基-β-亚氨基丙酸乙酯合成路线 (共 21 条)
反应条件
hydrogenchloride T=0°C; 4 h;
参考文献
Shenyang J and Health Pharmaceutical Co., Ltd.
Patent: EP2468730 A1, 2012 ;
Location in patent: Page/Page column 17 ;
反应条件
potassium carbonate in diethyl ether; water Yield given;
参考文献
CURIS, INC.
Patent: WO2008/33747 A2, 2008 ;
Location in patent: Page/Page column 254-255 ;
参考文献
Church, Timothy J.; Cutshall, Neil Scott; Gangloff, Anthony R.; Jenkins, Thomas E.; Linsell, Martin S.; Litvak, Joane; Rice, Kenneth D.; Spencer, Jeffrey R.; Wang, Vivian R.
Patent: US2001/53779 A1, 2001 ;
参考文献
Novartis Corporation
Patent: US5686457 A1, 1997 ;
US 5686457 A
反应条件
1: NH3 / ethanol / 4 h / Ambient temperature 2: 10 percent / NaHCO3 / ethanol / reflux, 5 min, r.t., 6 h. View Scheme
参考文献
Cocco; Congiu; Maccioni; Plumitallo; Schivo; Palmieri
Farmaco, Edizione Scientifica, 1988 , vol. 43, # 1 p. 103 - 112
反应条件
1: NH3 / ethanol / 4 h / Ambient temperature 2: 70 percent / NaHCO3 / ethanol / reflux, 5 min, r.t., 6 h. View Scheme
参考文献
Cocco; Congiu; Maccioni; Plumitallo; Schivo; Palmieri
Farmaco, Edizione Scientifica, 1988 , vol. 43, # 1 p. 103 - 112
反应条件
ammonia in ethanol 4 h; Ambient temperature;
参考文献
Cocco; Congiu; Maccioni; Plumitallo; Schivo; Palmieri
Farmaco, Edizione Scientifica, 1988 , vol. 43, # 1 p. 103 - 112
反应条件
in dichloromethane 10 h; Heating;
参考文献
Zhao, Mei-Xin; Wang, Mei-Xiang; Huang, Zhi-Tang
Tetrahedron, 2002 , vol. 58, # 7 p. 1309 - 1316
参考文献
Shaw; Woolley
Journal of Biological Chemistry, 1949 , vol. 181, p. 89,91
反应条件
formiate buffer (pH 3.51-4.18); water in acetonitrile T=25°C; other buffer; KineticsMechanism;
参考文献
Kavalek, Jaromir; Panchartek, Josef; Potesil, Tomas; Sterba, Vojeslav
Collection of Czechoslovak Chemical Communications, 1986 , vol. 51, # 3 p. 677 - 683