β-乙氧基-β-亚氨基丙酸乙酯合成路线 (共 21 条)
反应条件
ammonium chloride in ethanol 8 h; Heating;
参考文献
Kobayashi; Inoue; Kita; Yoshiya; Nishino; Oizumi; Kimura
Chemical and Pharmaceutical Bulletin, 1995 , vol. 43, # 5 p. 788 - 796
参考文献
Chemische Berichte, , vol. 73, p. 542,546
反应条件
sodium acetate; zinc 1.) acetic acid, 80 deg C, 40 min; 2.) acetic acid, 20 min, 95-105 deg C; Yield given. Multistep reaction;
参考文献
Lecas-Nawrocka, Alexandra; Levisalles, Jacques; Mariacher, Claire; Renko, Zafiarisoa; Rose, Eric
Canadian Journal of Chemistry, 1984 , vol. 62, p. 2054 - 2058
参考文献
Shenyang J and Health Pharmaceutical Co., Ltd.
Patent: EP2468730 A1, 2012 ;
Location in patent: Page/Page column 18 ;
反应条件
1.1: potassium carbonate / water / 0 °C 1.2: Reflux 2.1: sodium ethanolate / ethanol / 0.33 h / 0 °C / Inert atmosphere 2.2: 1.5 h / 60 °C View Scheme
参考文献
Kaspersen, Svein Jacob; Sorum, Christopher; Willassen, Veronica; Fuglseth, Erik; Kjobli, Eli; Bjorkoy, Geir; Sundby, Eirik; Hoff, Brd Helge
European Journal of Medicinal Chemistry, 2011 , vol. 46, # 12 p. 6002 - 6014
反应条件
1: NH3 / ethanol / 4 h / Ambient temperature 2: 80 percent / NaHCO3 / ethanol / reflux, 5 min, r.t., 6 h. View Scheme
参考文献
Cocco; Congiu; Maccioni; Plumitallo; Schivo; Palmieri
Farmaco, Edizione Scientifica, 1988 , vol. 43, # 1 p. 103 - 112
参考文献
Dornow; Karlson
Chemische Berichte, 1940 , vol. 73, p. 542,546
参考文献
Dornow; Karlson
Chemische Berichte, 1940 , vol. 73, p. 542,546
反应条件
in chloroform
T=20°C; 20 h;
参考文献
Walter, Harald
Zeitschrift fur Naturforschung - Section B Journal of Chemical Sciences, 2008 , vol. 63, # 4 p. 351 - 362
参考文献
Dornow; Hargesheimer
Chemische Berichte, 1953 , vol. 86, p. 461,464
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Dornow; Karlson
Chemische Berichte, 1940 , vol. 73, p. 542,546