3,5-二苄氧基苯甲酸甲酯合成路线 （共 24 条）
反应条件
1: 70 percent / ethanol; H2O / 3 h / Heating 2: 65 percent / aq. NaOH / ethanol / 48 h / Heating View Scheme
参考文献
Comber, Mark F.; Sargent, Melvyn V.; Skelton, Brian W.; White, Allan H.
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1989 , p. 441 - 448
反应条件
1: With silver benzoate; triethylamine in methanol Elimination; rearrangement; 2: With potassium hydroxide in methanol Hydrolysis;
参考文献
Freund, Ernst; Vitali, Francesca; Linden, Anthony; Robinson, John A.
Helvetica Chimica Acta, 2000 , vol. 83, # 9 p. 2572 - 2579
反应条件
1: 96 percent / K2CO3 / acetone / 12 h / Heating 2: 97 percent / LiAlH4 3: 84 percent / Et3N / CH2Cl2 / 0.33 h / 4 °C 4: 69 percent / benzyltriethylammonium chloride / H2O; CHCl3 / 2 h / Heating 5: 92 percent / aq. Ba(OH)2 / dioxane / 15 h / 115 °C View Scheme
参考文献
Resch, Verena; Lechner, Horst; Schrittwieser, Joerg H.; Wallner, Silvia; Gruber, Karl; MacHeroux, Peter; Kroutil, Wolfgang
Chemistry - A European Journal, 2012 , vol. 18, # 41 p. 13173 - 13179
反应条件
1.1: aq. KOH / ethanol / 20 °C 2.1: SOCl2 3.1: Et3N / tetrahydrofuran / 0 °C 4.1: silver benzoate; Et3N / methanol 4.2: aq. KOH / methanol View Scheme
参考文献
Freund, Ernst; Vitali, Francesca; Linden, Anthony; Robinson, John A.
Helvetica Chimica Acta, 2000 , vol. 83, # 9 p. 2572 - 2579
反应条件
1.1: Et3N / tetrahydrofuran / 0 °C 2.1: silver benzoate; Et3N / methanol 2.2: aq. KOH / methanol View Scheme
参考文献
Freund, Ernst; Vitali, Francesca; Linden, Anthony; Robinson, John A.
Helvetica Chimica Acta, 2000 , vol. 83, # 9 p. 2572 - 2579
反应条件
1.1: K2CO3 / dimethylformamide / 20 °C 2.1: aq. KOH / ethanol / 20 °C 3.1: SOCl2 4.1: Et3N / tetrahydrofuran / 0 °C 5.1: silver benzoate; Et3N / methanol 5.2: aq. KOH / methanol View Scheme
参考文献
Hill, Robert A.; Carter, Rachel H.; Staunton, James
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1981 , p. 2570 - 2576
反应条件
1.1: potassium carbonate; potassium iodide / acetone / 16 h / |Reflux 2.1: sodium hydroxide / water / 16 h / |Reflux 2.2: |Cooling with ice View Scheme
参考文献
Resch, Verena; Lechner, Horst; Schrittwieser, Joerg H.; Wallner, Silvia; Gruber, Karl; MacHeroux, Peter; Kroutil, Wolfgang
Chemistry - A European Journal, 2012 , vol. 18, # 41 p. 13173 - 13179
反应条件
(i) K2CO3, acetone, (ii) aq. KOH; Multistep reaction;
参考文献
Gerlach,H.
Helvetica Chimica Acta, 1977 , vol. 60, p. 3039 - 3044
反应条件
hydrogenchloride 16.5 h;
参考文献
Meltzer, Peter C.; Dalzell, Haldean C.; Razdan, Raj K.
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1981 , p. 2825 - 2829
反应条件
1: diethyl ether
2: 99 percent / 60percent HClO4 / H2O; acetic acid
3: 97 percent / H2 / Pd/C (5percent) / ethyl acetate; ethanol
4: CH3ONa / methanol
View Scheme
参考文献
Ichinose, Koji; Ebizuka, Yutaka; Sankawa, Ushio
Chemical and Pharmaceutical Bulletin, 1989 , vol. 37, # 10 p. 2873 - 2875
