1-(3-氯丙氧基)-4-碘苯合成路线 (共 3 条)
反应条件
potassium carbonate in acetone 20 h; Heating / reflux;
参考文献
BANYU PHARMACEUTICAL CO., LTD.
Patent: EP1820797 A1, 2007 ;
反应条件
1: 4-hydroxyiodobenzene With potassium carbonate in butanone 0.25 - 0.333333 h; 2: 1-bromo-3-chloro-propane T=25 - 30°C; 22.33 - 24.33 h; Heating / reflux; Product distribution / selectivity;
参考文献
GLAXO GROUP LIMITED
Patent: WO2007/71691 A1, 2007 ;
Location in patent: Page/Page column 38; 41 ;
WO 2007/071691 A1
反应条件
in N,N-dimethyl-formamide
参考文献
Kotobuki Pharmaceutical Co. Ltd.
Patent: US6124460 A1, 2000 ;