3-(3,4-二甲氧基苯基)-2-甲基-6-氧代己烷-3-甲腈合成路线 （共 4 条）
反应条件
1: 81 percent / 50percent aq. NaOH, Bu4NHSO4 / 5 h / 45 - 60 °C 2: 70 percent / NaNH2 / toluene / 5 h / Heating 3: oxalic acid / acetone; H2O / 3 h / 40 °C View Scheme
参考文献
Butora, Gabriel; Blaha, Ludvik; Rajsner, Miroslav; Helfert, Ivan
Collection of Czechoslovak Chemical Communications, 1992 , vol. 57, # 9 p. 1967 - 1981
反应条件
1: 70 percent / NaNH2 / toluene / 5 h / Heating 2: oxalic acid / acetone; H2O / 3 h / 40 °C View Scheme
参考文献
Butora, Gabriel; Blaha, Ludvik; Rajsner, Miroslav; Helfert, Ivan
Collection of Czechoslovak Chemical Communications, 1992 , vol. 57, # 9 p. 1967 - 1981
反应条件
1: With hydrogen; palladium 10 on activated carbon in ethanol T=40 - 45°C; 2: With sodium hydroxide in water 3: With hydrogenchloride in isopropyl alcohol
参考文献
ALBANI, Davide; Arosio, Roberto; Merli, Valeriano
Patent: US2009/171110 A1, 2009 ;
Location in patent: Page/Page column 6 ;
反应条件
formic acid in isopropyl alcohol; toluene
参考文献
BASF Aktiengesellschaft
Patent: US4350636 A1, 1982 ;
