1-丁基吡啶-2(1H)-酮合成路线 （共 16 条）
反应条件
chloro-trimethyl-silane; lithium hexamethyldisilazane in acetonitrile
T=50°C; Hilbert-Johnson reaction; P=4500450000 Torr; 96 h; Microwave irradiation;
参考文献
Iida, Hirokazu; Suda, Machiko; Nakajima, Etsuko; Hakamatsuka, Hiroko; Nagashima, Yuka; Joho, Kouta; Amemiya, Kenta; Moromizato, Tatsuya; Matsumoto, Kiyoshi; Murakami, Yasuoki; Hamana, Hiroshi
Heterocycles, 2010 , vol. 81, # 9 p. 2057 - 2062
反应条件
potassium carbonate; potassium iodide in methanol
Alkylation; 12 h; Heating;
参考文献
Sieburth, Scott McN.; Lin, Chao-Hsiung; Rucando, David
Journal of Organic Chemistry, 1999 , vol. 64, # 3 p. 950 - 953
反应条件
T=150°C; Hilbert-Johnson reaction; 0.0833333 h; Microwave irradiation;
参考文献
Iida, Hirokazu; Suda, Machiko; Nakajima, Etsuko; Hakamatsuka, Hiroko; Nagashima, Yuka; Joho, Kouta; Amemiya, Kenta; Moromizato, Tatsuya; Matsumoto, Kiyoshi; Murakami, Yasuoki; Hamana, Hiroshi
Heterocycles, 2010 , vol. 81, # 9 p. 2057 - 2062
反应条件
1: 2-hydroxy-pyridine With n-butyllithium
T=25°C; 0.5 h; Ionic liquidInert atmosphere;
2: n-butyl chloride T=25°C; 5 h; Ionic liquidInert atmosphere;
参考文献
Vavilina; Zicmanis; Mekss; Klavins
Chemistry of Heterocyclic Compounds, 2008 , vol. 44, # 5 p. 549 - 558
Khim. Geterotsikl. Soedin., 2008 , # 5 p. 699 - 710
反应条件
1: 2-hydroxy-pyridine With silver carbonate
T=25°C; 0.5 h; Ionic liquidInert atmosphere;
2: 1-iodo-butane T=25°C; 5 h; Ionic liquidInert atmosphere; TemperatureTimeReagent/catalystSolvent;
参考文献
Vavilina; Zicmanis; Mekss; Klavins
Chemistry of Heterocyclic Compounds, 2008 , vol. 44, # 5 p. 549 - 558
Khim. Geterotsikl. Soedin., 2008 , # 5 p. 699 - 710
反应条件
1: 2-hydroxy-pyridine With silver carbonate
T=25°C; 0.5 h; Ionic liquidInert atmosphere;
2: n-butyl p-toluenesulfonate T=25°C; 5 h; Ionic liquidInert atmosphere; Solvent;
参考文献
Vavilina; Zicmanis; Mekss; Klavins
Chemistry of Heterocyclic Compounds, 2008 , vol. 44, # 5 p. 549 - 558
Khim. Geterotsikl. Soedin., 2008 , # 5 p. 699 - 710
反应条件
potassium hydroxide
T=80°C; 6 h;
参考文献
Vavilina; Zicmanis; Mekss; Klavins
Chemistry of Heterocyclic Compounds, 2008 , vol. 44, # 5 p. 549 - 558
Khim. Geterotsikl. Soedin., 2008 , # 5 p. 699 - 710
反应条件
1: 2-hydroxy-pyridine With silver carbonate
T=25°C; 0.5 h; Ionic liquidInert atmosphere;
2: 1-bromo-butane T=25°C; 5 h; Ionic liquidInert atmosphere; SolventReagent/catalyst;
参考文献
Vavilina; Zicmanis; Mekss; Klavins
Chemistry of Heterocyclic Compounds, 2008 , vol. 44, # 5 p. 549 - 558
Khim. Geterotsikl. Soedin., 2008 , # 5 p. 699 - 710
反应条件
1: 2-hydroxy-pyridine With potassium hydroxide
T=25°C; 0.5 h; Ionic liquidInert atmosphere;
2: n-butyl chloride T=25°C; 5 h; Ionic liquidInert atmosphere; Reagent/catalystSolvent;
参考文献
Vavilina; Zicmanis; Mekss; Klavins
Chemistry of Heterocyclic Compounds, 2008 , vol. 44, # 5 p. 549 - 558
Khim. Geterotsikl. Soedin., 2008 , # 5 p. 699 - 710
反应条件
potassium hydroxide
T=25°C; 6 h;
参考文献
Vavilina; Zicmanis; Mekss; Klavins
Chemistry of Heterocyclic Compounds, 2008 , vol. 44, # 5 p. 549 - 558
Khim. Geterotsikl. Soedin., 2008 , # 5 p. 699 - 710
