1,6-二苯基-3-己烯-1,5-二炔合成路线 （共 12 条）
反应条件
cyclohexa-1,4-diene in benzene T=280°C; Bergman cyclization; 3 h; Product distribution; Further Variations:Temperatures;
参考文献
Journal of the American Chemical Society, , vol. 127, # 28 p. 9968 - 9969
反应条件
T=1000°C; P=0.02 Torr; Product distribution; Further Variations:Temperatures;
参考文献
Journal of Physical Organic Chemistry, , vol. 17, # 9 p. 798 - 806
反应条件
cyclohexa-1,4-diene in benzene T=280°C; Bergman cyclization; 3 h; Product distribution; Further Variations:Temperatures;
参考文献
Journal of the American Chemical Society, , vol. 127, # 28 p. 9968 - 9969
反应条件
copper(l) iodide; N-butylamine; tetrakis(triphenylphosphine) palladium(0) in benzene
T=20°C; 3 h;
参考文献
Polishchuk, Alexei L.; Bartlett, Kevin L.; Friedman, Lee A.; Jones Jr., Maitland
Journal of Physical Organic Chemistry, 2004 , vol. 17, # 9 p. 798 - 806
反应条件
copper(l) iodide; tetrakis(triphenylphosphine) palladium(0); N-butylamine in benzene
T=20°C; Sonogashira coupling; 24 h;
参考文献
Kosinski, Christoph; Hirsch, Andreas; Heinemann, Frank W.; Hampel, Frank
European Journal of Organic Chemistry, 2001 , # 20 p. 3879 - 3890
反应条件
N,N,N',N',N'',N''-hexamethylphosphoric triamide; lithium hexamethyldisilazane in tetrahydrofuran
T=-95°C; Addition;
参考文献
Jones, Graham B.; Wright, Justin M.; Plourde, Gary W.; Hynd, George; Huber, Robert S.; Mathews, Jude E.
Journal of the American Chemical Society, 2000 , vol. 122, # 9 p. 1937 - 1944
反应条件
1: Ph3P; CBr4 / benzene / 2 h / 0 °C
2: 95 percent / Na2S / methanol / 2 h / 20 °C
3: 89 percent / Oxone / CH2Cl2 / 50 °C
4: 30 percent / KOH-Al2O3; CBr2F2 / CH2Cl2
View Scheme
参考文献
Cao, Xiaoping; Yang, Yuying; Wang, Xiaolong
Journal of the Chemical Society. Perkin Transactions 1, 2002 , # 22 p. 2485 - 2489
反应条件
1: BuLi
2: Br2; PPh3
3: lithium hexamethyldisilazane; HMPA / tetrahydrofuran / -95 °C
View Scheme
参考文献
Jones, Graham B.; Wright, Justin M.; Plourde, Gary W.; Hynd, George; Huber, Robert S.; Mathews, Jude E.
Journal of the American Chemical Society, 2000 , vol. 122, # 9 p. 1937 - 1944
反应条件
N-butylamine; copper(l) iodide; tetrakis(triphenylphosphine) palladium(0) in benzene
1 h; Ambient temperature;
参考文献
Vollhardt, K. Peter C.; Winn, Libbie S.
Tetrahedron Letters, 1985 , vol. 26, # 6 p. 709 - 712
反应条件
1: 89 percent / Oxone / CH2Cl2 / 50 °C
2: 30 percent / KOH-Al2O3; CBr2F2 / CH2Cl2
View Scheme
参考文献
Cao, Xiaoping; Yang, Yuying; Wang, Xiaolong
Journal of the Chemical Society. Perkin Transactions 1, 2002 , # 22 p. 2485 - 2489
