4-(1,3-苯并恶唑-2-基)苯甲醛合成路线 （共 5 条）
反应条件
1: NBS, (PhCO2)2 / CCl4 / 5 h / Heating 2: (i) hexamethylenetetramine, CHCl3, (ii) aq. AcOH View Scheme
参考文献
DSM IP ASSETS B.V.
Patent: WO2004/256 A1, 2003 ;
Location in patent: Page 20 ;
反应条件
PdCl(C3H5)(dppb); caesium carbonate in carbonic acid diethyl ester T=130°C; 17 h; Inert atmosphere; regioselective reaction;
参考文献
Dong, Jia Jia; Roger, Julien; Verrier, Cecile; Martin, Thibaut; Le Goff, Ronan; Hoarau, Christophe; Doucet, Henri
Green Chemistry, 2010 , vol. 12, # 11 p. 2053 - 2063
反应条件
hydrogen; Pd-BaSO4; quinoline S in xylene Heating; Yield given;
参考文献
Erckel, R.; Fruehbeis, H.
Zeitschrift fuer Naturforschung, Teil B: Anorganische Chemie, Organische Chemie, 1982 , vol. 37, # 11 p. 1472 - 1480
反应条件
[2,2']bipyridinyl; potassium phosphate; Ni2(BDC)2(1,4-diazabicyclo[2.2.2]octane) in N,N-dimethyl acetamide T=100°C; 3 h;
参考文献
Phan, Nam T. S.; Nguyen, Chung K.; Nguyen, Tung T.; Truong, Thanh
Catalysis Science and Technology, 2014 , vol. 4, # 2 p. 369 - 377
反应条件
(i) hexamethylenetetramine, CHCl3, (ii) aq. AcOH; Multistep reaction;
参考文献
Thomas,D.A.
Journal of Heterocyclic Chemistry, 1970 , vol. 7, p. 457 - 462
