1,3-苯并间二氧杂环戊烯合成路线 （共 145 条）
反应条件
oxygen; sodium carbonate; acetylacetone; palladium diacetate in propionic acid
T=90°C; P=760.051 Torr; 1 h;
参考文献
Yamada, Tomoyuki; Sakaguchi, Satoshi; Ishii, Yasutaka
Journal of Organic Chemistry, 2005 , vol. 70, # 14 p. 5471 - 5474
反应条件
in ethanol; dichloromethane
T=20°C; 10 h; Irradiationvarious solvents; the effects of ethanol, temperature, and reaction time; Product distribution;
参考文献
Butts, Craig P.; Eberson, Lennart; Hartshorn, Michael P.; Persson, Ola
Acta Chemica Scandinavica, 1997 , vol. 51, # 6-7 p. 718 - 732
反应条件
1: 98 percent / TiCl4 / CH2Cl2 / -20 °C
2: 65 percent / Bu3SnH, azoisobutyronitrile / benzene / Heating
View Scheme
参考文献
Ishibashi; Mino; Sakata; Inada; Ikeda
Chemical and Pharmaceutical Bulletin, 1991 , vol. 39, # 5 p. 1148 - 1151
反应条件
sodium iodide in acetonitrile
6 h; Ambient temperature; Product distribution;
参考文献
Corda, Luciana; Fadda, Anna Maria; Maccioni, Antonio; Maccioni, Anna Maria; Podda, Gianni
Journal of Heterocyclic Chemistry, 1988 , vol. 25, p. 311 - 314
反应条件
nitric acid
T=25°C; 1 h;
参考文献
Takakis, Ioannis M.; Hadjimihalakis, Phaedon M.
Journal of Heterocyclic Chemistry, 1991 , vol. 28, # 3 p. 625 - 634
反应条件
sodium hydride in N,N,N',N',N'',N''-hexamethylphosphoric triamide; benzene
24 h; Heating;
参考文献
Melis, Stefana; Monni, Francesca; Piras, Pier Paolo; Sotgiu, Francesca
Journal of Heterocyclic Chemistry, 1983 , vol. 20, p. 463
反应条件
1: With bis(acetylacetonate)nickel(II); potassium phosphate; triphenylphosphine
0.0833333 h; Inert atmosphereSchlenk technique;
2: With di-tert-butyl peroxide
T=100°C; 16 h; Inert atmosphereSchlenk technique;
参考文献
Liu, Dong; Liu, Chao; Li, Heng; Lei, Aiwen
Angewandte Chemie - International Edition, 2013 , vol. 52, # 16 p. 4453 - 4456
反应条件
1.1: 90 percent / N-bromosuccinimide / CHCl3 / 3.5 h / Heating
2.1: n-BuLi / diethyl ether; hexane / 0.17 h / -30 °C
2.2: 80 percent / tetrahydrofuran; diethyl ether; hexane / 2 h / 20 °C
3.1: 97 percent / 1,8-diazabicyclo[5.4.0]undec-7-ene; POCl3 / pyridine / 20 - 80 °C
4.1: H2 / Pd/C / methanol; tetrahydrofuran / 20 h
5.1: conc. sulfuric acid / tetrahydrofuran; H2O / 1.5 h
View Scheme
参考文献
Magnus; Bailey; Porter
Tetrahedron, 1999 , vol. 55, # 49 p. 13927 - 13936
反应条件
aluminium trichloride in dichloromethane
T=20°C; Friedel-Crafts acylation; 1 h;
参考文献
Ianni, Alen; Waldvogel, Siegfried R.
Synthesis, 2006 , # 13 p. 2103 - 2112
反应条件
aluminium trichloride
参考文献
Podda, G.; Maccioni, A.; Fadda, A.; Daolio, S.; Traldi, P.; Vecchi, E.
Organic Mass Spectrometry, 1983 , vol. 18, # 7 p. 318 - 320
