咪唑并[1,5-a]吡啶合成路线 （共 16 条）
反应条件
trichlorophosphate; benzene
参考文献
Pfizer Inc.
Patent: US4097598 A1, 1978 ;
Title/Abstract Full Text Show Details
Pfizer Inc.
Patent: US4044015 A1, 1977 ;
反应条件
sodium hydroxide; formic acid in trichlorophosphate
参考文献
Pfizer Inc.
Patent: US4097598 A1, 1978 ;
反应条件
sodium hydroxide; tetra-n-propylammonium bromide in ethylene glycol dimethyl ether T=50°C; 4.5 h; Product distribution;
参考文献
Langry, Kevin C.
Journal of Organic Chemistry, 1991 , vol. 56, # 7 p. 2400 - 2404
反应条件
2: POCl3; benzene View Scheme
参考文献
Bower; Ramage
Journal of the Chemical Society, 1955 , p. 2834,2836
反应条件
1: imidazo(1,5-a)pyridine With n-butyllithium in tetrahydrofuran; hexane T=-40°C; 3.5 h; 2: N,N-dimethyl-formamide in tetrahydrofuran; hexane T=25°C; 3: With water in tetrahydrofuran; hexane
参考文献
DeGoey, David A.; Flentge, Charles A.; Flosi, William J.; Grampovnik, David J.; Kempf, Dale J.; Klein, Larry L.; Yeung, Ming C.; Randolph, John T.; Wang, Xiu C.; Yu, Su
Patent: US2005/148623 A1, 2005 ;
Location in patent: Page/Page column 150 ;
US 20050148623 A1
反应条件
hydrogenchloride; sodium nitrite
参考文献
Paudler,W.W.; Kuder,J.E.
Journal of Organic Chemistry, 1967 , vol. 32, p. 2430 - 2433
反应条件
tetra-n-butylammonium acetate; palladium diacetate; triphenylphosphine in toluene T=100°C; Inert atmosphere; regioselective reaction;
参考文献
Huang, Chunhui; Giokaris, Alexandros; Gevorgyan, Vladimir
Chemistry Letters, 2011 , vol. 40, # 9 p. 1053 - 1054
反应条件
[Pd(phen)2(PF6)2]; caesium carbonate in dimethylammonium 2,4-dichlorophenoxyacetate T=150°C; 20 h; Inert atmosphere; regioselective reaction;
参考文献
Yamaguchi, Eiji; Shibahara, Fumitoshi; Murai, Toshiaki
Chemistry Letters, 2011 , vol. 40, # 9 p. 939 - 940
反应条件
hydrogenchloride in tetrahydrofuran; hexane
参考文献
Love, Christopher; Van Wauwe, Jean Pierre Frans; De Brabander, Marc; Cooymans, Ludwig; Vandermaesen, Nele; Kennis, Ludo Edmond Josephine
Patent: US2003/203897 A1, 2003 ;
反应条件
carbon disulfide; aluminium trichloride
参考文献
Bower; Ramage
Journal of the Chemical Society, 1955 , p. 2834,2836
