[1,2,4]噻唑[4,3-a]吡嗪合成路线 (共 3 条)
反应条件
hydrogen; palladium on activated charcoal in ethanol P=760 Torr; 2 h;
参考文献
Hardy, Christopher R.; Parrick, John
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1980 , p. 506 - 511
参考文献
MERCK and CO., INC.
Patent: WO2004/58266 A1, 2004 ;
Location in patent: Page/Page column 79 ;
WO 2004/058266 A1
反应条件
1: 15 percent / hydrogen peroxide / acetic acid / 2 h / 70 - 80 °C
2: 17 percent / sodium acetate, acetic anhydride / 0.5 h / Heating
View Scheme
参考文献
Hardy, Christopher R.; Parrick, John
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1980 , p. 506 - 511