L-(-)-二苯甲酰酒石酸合成路线 （共 16 条）
反应条件
sodium hydroxide in water; ethyl acetate T=0°C; 0.25 h;
参考文献
Krsek, George R.; Durazo, Enrique E.
Patent: US2005/171155 A1, 2005 ;
Location in patent: Page/Page column 3 ;
反应条件
chiral stationary phase including (R)-naphthylethyl-carbamate-functionalized CF6 in methanol; acetic acid; triethylamine; acetonitrile T=20°C; Resolution of racemate; Purification / work up;
参考文献
Sun, Ping; Wang, Chunlei; Breitbach, Zachary S.; Zhang, Ying; Armstrong, Daniel W.
Analytical Chemistry, 2009 , vol. 81, # 24 p. 10215 - 10226
反应条件
sulfuric acid in 1,4-dioxane T=100 - 102°C; 3 h;
参考文献
Bernas, Urszula; Hajmowicz, Halina; Madura, Izabela D.; Majcher, Monika; Synoradzki, Ludwik; Zawada, Krzysztof
Arkivoc, 2010 , vol. 2010, # 11 p. 1 - 12
反应条件
sulfuric acid in acetonitrile T=47°C;
参考文献
Bernas, Urszula; Hajmowicz, Halina; Madura, Izabela D.; Majcher, Monika; Synoradzki, Ludwik; Zawada, Krzysztof
Arkivoc, 2010 , vol. 2010, # 11 p. 1 - 12
参考文献
Mravik, Andras; Lepp, Zsolt; Fogassy, Elemer
Tetrahedron Asymmetry, 1996 , vol. 7, # 8 p. 2387 - 2390
Title/Abstract Full Text View citing articles Show Details
Elekes, Ferenc; Kovari, Zoltan; Mravik, Andras; Boecskei, Zsolt; Fogassy, Elemer
Tetrahedron Asymmetry, 1998 , vol. 9, # 16 p. 2895 - 2900
参考文献
Davenport, Kenneth G.; Mao, David T.; Richmond, Cliff M.; Bergbreiter, David E.; Newcomb, Martin
Journal of Chemical Research, Miniprint, 1984 , # 5 p. 1518 - 1530
反应条件
water in water byproducts: acetic acid; stoich. amts., refluxing for 3.5 h (periodical evapn. of AcOH); collection (hot filtration), washing (water, EtOH, ether), drying (vac.);
参考文献
McCann, Malachy; Humphreys, Fergal; McKee, Vickie
Polyhedron, 1997 , vol. 16, # 20 p. 3655 - 3661
反应条件
chiral stationary phase including (R)-naphthylethyl-carbamate-functionalized CF6 in methanol; acetic acid; triethylamine; acetonitrile T=20°C; Resolution of racemate; Purification / work up;
参考文献
Sun, Ping; Wang, Chunlei; Breitbach, Zachary S.; Zhang, Ying; Armstrong, Daniel W.
Analytical Chemistry, 2009 , vol. 81, # 24 p. 10215 - 10226
参考文献
Mravik, Andras; Lepp, Zsolt; Fogassy, Elemer
Tetrahedron Asymmetry, 1996 , vol. 7, # 8 p. 2387 - 2390
Title/Abstract Full Text View citing articles Show Details
Elekes, Ferenc; Kovari, Zoltan; Mravik, Andras; Boecskei, Zsolt; Fogassy, Elemer
Tetrahedron Asymmetry, 1998 , vol. 9, # 16 p. 2895 - 2900
参考文献
XENOPORT, INC.
Patent: WO2005/66122 A2, 2005 ;
Location in patent: Page/Page column 51 ;
