1: toluene / 6 h / Heating 2: 0.55 g / n-butyllithium / hexane; tetrahydrofuran / 16 h / -78 °C View Scheme
参考文献
Pettit, George R.; Grealish, Matthew P.; Jung, M. Katherine; Hamel, Ernest; Pettit, Robin K.; Chapuis, J.-Charles; Schmidt, Jean M.
Journal of Medicinal Chemistry, 2002 , vol. 45, # 12 p. 2534 - 2542
1.1: 10 h / Heating 2.1: NaOMe; tetrabutylammonium iodide / dimethylformamide / 1 h / 20 °C 2.2: 60.7 percent / dimethylformamide / 8 h / 40 °C 3.1: 90 percent / BBr3 / CH2Cl2 / 2 h / 20 °C View Scheme
参考文献
Pettit, George R.; Grealish, Matthew P.; Jung, M. Katherine; Hamel, Ernest; Pettit, Robin K.; Chapuis, J.-Charles; Schmidt, Jean M.
Journal of Medicinal Chemistry, 2002 , vol. 45, # 12 p. 2534 - 2542
Huttrer et al.
Journal of the American Chemical Society, 1946 , vol. 68, p. 1999,2000
Full Text Show Details
Soc. Usines Chim. Rhone-Poulenc
Patent: DE880749 , 1943 ;
DRP/DRBP Org.Chem.
Full Text Show Details
Soc. Usines Chim. Rhone-Poulenc
Patent: US2502151 , 1946 ;