7,8-二氢-2-甲基-5(6H)-喹啉酮合成路线 （共 7 条）
反应条件
in N,N-dimethyl-formamide
T=100 - 150°C; 6 h;
参考文献
MERCK and CO., INC.
Patent: WO2006/60344 A2, 2006 ;
Location in patent: Page/Page column 21 ;
WO 2006/060344 A2
反应条件
chloro-trimethyl-silane; titanium tetrachloride; lithium; cesium fluoride in tetrahydrofuran
24 h; Heating;
参考文献
Mori, Miwako; Akashi, Masaya; Hori, Masanori; Hori, Katsutoshi; Nishida, Mayumi; Sato, Yoshihiro
Bulletin of the Chemical Society of Japan, 2004 , vol. 77, # 9 p. 1655 - 1670
反应条件
in N,N-dimethyl-formamide
T=70 - 80°C; 3 h;
参考文献
Tang, Weijun; Sun, Yawei; Lijin, Xu; Wang, Tianli; Qinghua Fan; Lam, Kim-Hung; Chan, Albert S.C.
Organic and Biomolecular Chemistry, 2010 , vol. 8, # 15 p. 3464 - 3471
参考文献
John Wyeth and Brother Limited
Patent: US3998831 A1, 1976 ;
参考文献
John Wyeth and Brother Limited
Patent: US3998831 A1, 1976 ;
参考文献
John Wyeth and Brother Limited
Patent: US4092317 A1, 1978 ;
反应条件
palladium on activated charcoal in toluene
96 h; Heating;
参考文献
Nitta; Soeda; Iino
Bulletin of the Chemical Society of Japan, 1990 , vol. 63, # 3 p. 932 - 934
