1.1: potassium carbonate / N,N-dimethyl-formamide / 2 h / 10 °C 2.1: lithium aluminium tetrahydride / tetrahydrofuran / 1.5 h / 0 - 10 °C 2.2: 0 °C 3.1: hydrogen / palladium 10 on activated carbon / methanol / 2 h / 40 °C / 3677.86 - 4413.43 Torr View Scheme

1: With borane-THF; (R)-tetrahydro-1-methyl-3,3-diphenyl-1H,3H-pyrrolo[1,2-c]-[1,3,2]oxazaborole in tetrahydrofuran T=20°C; 1.75 h; 2: With methanol in tetrahydrofuran

N-bromosuccinmide; sulfuric acid in acetonitrile T=50°C; 1 h;

1: 55 percent / Na / ethanol / 30 h / Heating 2: 78 percent / AlCl3, bromine / diethyl ether / 3 h / Ambient temperature View Scheme

1: potassium carbonate / potassium iodide / N,N-dimethyl-formamide / 2 h / 50 - 65 °C 2: N-bromosuccinmide; sulfuric acid / acetonitrile / 1 h / 50 °C View Scheme

暂无反应条件数据

1: potassium carbonate / acetonitrile 2: bromine / chloroform View Scheme