1-甲基-4-丙-1-炔基苯合成路线 （共 19 条）
反应条件
hydrogenchloride; zinc(II) chloride in dichloromethane 1 h; Ambient temperature; Product distributionMechanism;
参考文献
Chemische Berichte, , vol. 116, # 2 p. 777 - 797
反应条件
lanthanum; iodine in tetrahydrofuran
T=67°C; Fritsch-Buttenberg-Wiechell rearrangement; 3 h; Inert atmosphere;
参考文献
Umeda, Rui; Yuasa, Takumi; Anahara, Namika; Nishiyama, Yutaka
Journal of Organometallic Chemistry, 2011 , vol. 696, # 9 p. 1916 - 1919
反应条件
lanthanum; iodine in tetrahydrofuran
T=67°C; Fritsch-Buttenberg-Wiechell rearrangement; 3 h; Inert atmosphere;
参考文献
Umeda, Rui; Yuasa, Takumi; Anahara, Namika; Nishiyama, Yutaka
Journal of Organometallic Chemistry, 2011 , vol. 696, # 9 p. 1916 - 1919
反应条件
bis-triphenylphosphine-palladium(II) chloride; 1,8-diazabicyclo[5.4.0]undec-7-ene; 1,4-di(diphenylphosphino)-butane in dimethyl sulfoxide
T=80°C; 12 h; Inert atmosphere;
参考文献
Okuno, Yuri; Yamashita, Makoto; Nozaki, Kyoko
European Journal of Organic Chemistry, 2011 , # 20-21 p. 3951 - 3958
反应条件
n-butyllithium in tetrahydrofuran; N,N,N',N',N'',N''-hexamethylphosphoric triamide
T=20°C; 3 h;
参考文献
Hanack, Michael; Weber, Erhard
Chemische Berichte, 1983 , vol. 116, # 2 p. 777 - 797
反应条件
t-Bu-XantPhos; dichloro bis(acetonitrile) palladium(II); potassium carbonate; cesium fluoride in toluene
T=100°C; 20 h; Inert atmosphere;
参考文献
Liu, Yan-Yun; Yang, Xu-Heng; Huang, Xiao-Cheng; Wei, Wen-Ting; Song, Ren-Jie; Li, Jin-Heng
Journal of Organic Chemistry, 2013 , vol. 78, # 20 p. 10421 - 10426
反应条件
copper(l) iodide; triethylamine; bis-triphenylphosphine-palladium(II) chloride
24 deg C, then 65 deg C;
参考文献
Pschirer, Neil Gregory; Bunz, Uwe H. F.
Tetrahedron Letters, 1999 , vol. 40, # 13 p. 2481 - 2484
反应条件
1: 76 percent / PCl5 / 12 h / 20 °C
2: 53 percent / KOH / ethanol / Heating
3: 1.) Li, Fe(NO3)3 / 1.) liq.NH3, HMPA, 30 min; 2.) 6 h
View Scheme
参考文献
Mesnard, Danielle; Bernadou, Francoise; Miginiac, Leone
Journal of Chemical Research, Miniprint, 1981 , # 9 p. 3216 - 3245
反应条件
1: 79 percent / PCl5 / benzene / 48 h / Heating
2: 77 percent / Mg, 1,2-dibromoethane / tetrahydrofuran / Heating
View Scheme
参考文献
Engler, Thomas A.; Combrink, Keith D.; Ray, James E.
Synthetic Communications, 1989 , vol. 19, # 9-10 p. 1735 - 1744
反应条件
1: 53 percent / KOH / ethanol / Heating
2: 1.) Li, Fe(NO3)3 / 1.) liq.NH3, HMPA, 30 min; 2.) 6 h
View Scheme
参考文献
Mesnard, Danielle; Bernadou, Francoise; Miginiac, Leone
Journal of Chemical Research, Miniprint, 1981 , # 9 p. 3216 - 3245
