pyridine; aluminium trichloride in ethyl acetate T=77°C; 2 h;

1: 93 percent / diethyl ether; tetrahydrofuran / 1 h / 20 °C 2: 91 percent / NaO-tBu; cyclohexanone / toluene / 0.5 h / Heating 3: 94 percent / ammonium formate / 10percent Pd/C / methanol / 0.5 h / Heating 4: 71 percent / 70percent HNO3; AcOH / 0.5 h / 20 °C 5: 99 percent / AlCl3; pyridine / ethyl acetate / 2 h / Heating View Scheme

1: 94 percent / ammonium formate / 10percent Pd/C / methanol / 0.5 h / Heating 2: 71 percent / 70percent HNO3; AcOH / 0.5 h / 20 °C 3: 99 percent / AlCl3; pyridine / ethyl acetate / 2 h / Heating View Scheme

1: 91 percent / NaO-tBu; cyclohexanone / toluene / 0.5 h / Heating 2: 94 percent / ammonium formate / 10percent Pd/C / methanol / 0.5 h / Heating 3: 71 percent / 70percent HNO3; AcOH / 0.5 h / 20 °C 4: 99 percent / AlCl3; pyridine / ethyl acetate / 2 h / Heating View Scheme

1: 93 percent / K2CO3 / acetone / 2 h / Heating 2: 93 percent / diethyl ether; tetrahydrofuran / 1 h / 20 °C 3: 91 percent / NaO-tBu; cyclohexanone / toluene / 0.5 h / Heating 4: 94 percent / ammonium formate / 10percent Pd/C / methanol / 0.5 h / Heating 5: 71 percent / 70percent HNO3; AcOH / 0.5 h / 20 °C 6: 99 percent / AlCl3; pyridine / ethyl acetate / 2 h / Heating View Scheme

1: 71 percent / 70percent HNO3; AcOH / 0.5 h / 20 °C 2: 99 percent / AlCl3; pyridine / ethyl acetate / 2 h / Heating View Scheme

1: 95 percent / Mg / diethyl ether; tetrahydrofuran 2: 96 percent / Na2Cr2O7; aq. H2SO4; Bu4NBr / CH2Cl2 3: 91 percent / HBr; AcOH / CH2Cl2 4: 72 percent / HNO3; AcOH 5: 99.4 percent / AlCl3; Py / ethyl acetate / 2 h / 77 °C View Scheme