3-氨基吡啶-2-甲酸乙酯合成路线 （共 13 条）
反应条件
sulfuric acid 48 h; Heating;
参考文献
Carpino, Louis A.; Xia, Jusong; El-Faham, Ayman
Journal of Organic Chemistry, 2004 , vol. 69, # 1 p. 54 - 61
反应条件
sulfuric acid; dihydrogen peroxide; iron(II) sulfate 1.) 0-5 deg C, water; Yield given. Multistep reaction. Yields of byproduct given;
参考文献
Min, R. S.; Aksenov, V. S.
Chemistry of Heterocyclic Compounds (New York, NY, United States), 1988 , vol. 24, # 8 p. 885 - 886
Khimiya Geterotsiklicheskikh Soedinenii, 1988 , # 8 p. 1075 - 1077
参考文献
Oakes et al.
Journal of the Chemical Society, 1956 , p. 1045,1053
反应条件
1: 90 percent / hydroxylamine hydrochloride; sodium hydroxide / H2O; methanol / 48 h 2: 20 percent / NaNO2; HCl / H2O / 0.5 h / 5 °C View Scheme
参考文献
Carpino, Louis A.; Xia, Jusong; El-Faham, Ayman
Journal of Organic Chemistry, 2004 , vol. 69, # 1 p. 54 - 61
反应条件
sulfuric acid; bromine; acetic acid in water 0.25 h;
参考文献
WO2012/74951 A1, ;
Page/Page column 46-47 ;
WO 2012/074951 A1
反应条件
1: 81 percent / pyridine / toluene / 2 h / Heating 2: 43 percent / KH / toluene; dimethylformamide / 70 °C View Scheme
参考文献
Kunick, Conrad; Lauenroth, Kathrin; Leost, Maryse; Meijer, Laurent; Lemcke, Thomas
Bioorganic and Medicinal Chemistry Letters, 2004 , vol. 14, # 2 p. 413 - 416
反应条件
1: 7.2 g / LiAlH4 / tetrahydrofuran / 1 h 2: 82 percent / MnO2 / CHCl3 / 24 h / Ambient temperature View Scheme
参考文献
Chen; Deady
Journal of Heterocyclic Chemistry, 1992 , vol. 29, # 5 p. 1197 - 1201
反应条件
lithium aluminium tetrahydride in tetrahydrofuran 1 h;
参考文献
Chen; Deady
Journal of Heterocyclic Chemistry, 1992 , vol. 29, # 5 p. 1197 - 1201
反应条件
1: 81 percent / pyridine / toluene / 2 h / Heating 2: 43 percent / KH / toluene; dimethylformamide / 70 °C 3: 95 percent / H2O / dimethylformamide / 150 °C View Scheme
参考文献
Kunick, Conrad; Lauenroth, Kathrin; Leost, Maryse; Meijer, Laurent; Lemcke, Thomas
Bioorganic and Medicinal Chemistry Letters, 2004 , vol. 14, # 2 p. 413 - 416
反应条件
pyridine in toluene 2 h; Heating;
参考文献
Kunick, Conrad; Lauenroth, Kathrin; Leost, Maryse; Meijer, Laurent; Lemcke, Thomas
Bioorganic and Medicinal Chemistry Letters, 2004 , vol. 14, # 2 p. 413 - 416
