3-氨基吡啶-2-甲酸乙酯合成路线 （共 13 条）
参考文献
Oakes et al.
Journal of the Chemical Society, 1956 , p. 1045,1053
反应条件
1: 90 percent / hydroxylamine hydrochloride; sodium hydroxide / H2O; methanol / 48 h
2: 32 percent / NaNO2; HCl / H2O / 0.5 h / 5 °C
View Scheme
参考文献
Carpino, Louis A.; Xia, Jusong; El-Faham, Ayman
Journal of Organic Chemistry, 2004 , vol. 69, # 1 p. 54 - 61
反应条件
1: 81 percent / pyridine / toluene / 2 h / Heating
2: 43 percent / KH / toluene; dimethylformamide / 70 °C
3: 95 percent / H2O / dimethylformamide / 150 °C
4: 75 percent / HCl; NaOAc / acetic acid / 70 °C
View Scheme
参考文献
Kunick, Conrad; Lauenroth, Kathrin; Leost, Maryse; Meijer, Laurent; Lemcke, Thomas
Bioorganic and Medicinal Chemistry Letters, 2004 , vol. 14, # 2 p. 413 - 416
