四氢-2-氧代-3-呋喃甲腈合成路线 （共 8 条）
反应条件
1: 75 percent / Rh2(OAc)4 / 1,2-dichloro-ethane / 1 h / Heating 2: conc. HCl / methanol View Scheme
参考文献
Yamagata, Kenji; Okabe, Fumi; Yamazaki, Motoyoshi
Advanced Synthesis and Catalysis, 1999 , vol. 341, # 6 p. 562 - 567
反应条件
manganese triacetate in acetic acid T=70°C; 0.166667 h;
参考文献
Fristad, William E.; Peterson, John R.; Ernst, Andreas B.
Journal of Organic Chemistry, 1985 , vol. 50, # 17 p. 3143 - 3148
参考文献
Mazal, Ctibor; Jonas, Jaroslav; Zak, Zdirad
Tetrahedron, 2002 , vol. 58, # 14 p. 2729 - 2733
反应条件
ethanol; sodium ethanolate
参考文献
Feofilaktow; Onischtschenko
Zhurnal Obshchei Khimii, 1939 , vol. 9, p. 325,329
Chem. Zentralbl., 1939 , vol. 110, # II p. 3080
反应条件
thiourea in ethanol; water
参考文献
Pharmacia and Upjohn Company
Patent: US6043248 A1, 2000 ;
反应条件
sodium ethanolate in ethanol
Heating;
参考文献
Albrecht,R.; Schumann,K.
European Journal of Medicinal Chemistry, 1976 , vol. 11, p. 155 - 158
反应条件
1: NaOEt / ethanol / Heating
2: H2SO4 / 100 °C
View Scheme
参考文献
Albrecht,R.; Schumann,K.
European Journal of Medicinal Chemistry, 1976 , vol. 11, p. 155 - 158
反应条件
1: NaOEt / ethanol / Heating
2: H2SO4 / 100 °C
3: (i) H2SO4, (heating), (ii) HNO3, H2SO4
4: aq. HCl / Heating
View Scheme
参考文献
Albrecht,R.; Schumann,K.
European Journal of Medicinal Chemistry, 1976 , vol. 11, p. 155 - 158
