7-氮杂双环[2,2,1]庚烷盐酸盐合成路线 （共 14 条）
反应条件
triethylamine in dichloromethane T=0°C;
参考文献
Otani, Yuko; Nagae, Osamu; Naruse, Yuji; Inagaki, Satoshi; Ohno, Masashi; Yamaguchi, Kentaro; Yamamoto, Gaku; Uchiyama, Masanobu; Ohwada, Tomohiko
Journal of the American Chemical Society, 2003 , vol. 125, # 49 p. 15191 - 15199
反应条件
sodium hydroxide 0.25 h;
参考文献
Davis, Charles R.; Johnson, Roy A.; Cialdella, Joyce I.; Liggett, Walter F.; Mizsak, Stephen A.; Marshall, Vincent P.
Journal of Organic Chemistry, 1997 , vol. 62, # 7 p. 2244 - 2251
反应条件
N-ethyl-N,N-diisopropylamine in tetrahydrofuran; N,N-dimethyl acetamide
T=160°C; 0.333333 h;
参考文献
ARENA PHARMACEUTICALS, INC.
Patent: WO2007/120600 A2, 2007 ;
Location in patent: Page/Page column 84-85 ;
WO 2007/120600 A2
反应条件
triethylamine in dichloromethane
T=20°C; 18 h;
参考文献
ASTRAZENECA AB; ASTRAZENECA UK LIMITED
Patent: WO2007/7041 A1, 2007 ;
Location in patent: Page/Page column 208-209 ;
WO 2007/007041 A1
