叔-丁基N-[(1S)-1-(羟基甲基)丙-2-炔基]氨基甲酸酯合成路线 (共 2 条)
反应条件
p-toluenesulfonic acid monohydrate in methanol; water
参考文献
Hoffmann-La Roche Inc.
Patent: US6130239 A1, 2000 ;
US 6130239 A
反应条件
sodium carbonate in 1,4-dioxane; water T=0°C; Title compound not separated from byproducts;
参考文献
Meffre, Patrick; Gauzy, Laurence; Perdigues, Chantal; Desanges-Levecque, Florence; Branquet, Eric; Durand, Philippe; Le Goffic, Francois
Tetrahedron Letters, 1995 , vol. 36, # 6 p. 877 - 880