3,3-氧杂环丁烷二甲醇合成路线 （共 15 条）
参考文献
Issidorides; Matar
Journal of the American Chemical Society, 1955 , vol. 77, p. 6382
反应条件
pyridine in chloroform
63 h;
参考文献
Fredriksen, Siw B.; Dale, Johannes
Acta Chemica Scandinavica, 1992 , vol. 46, # 6 p. 574 - 588
反应条件
1.1: sodium hydride / tetrahydrofuran / 1 h / |Inert atmosphere; |Cooling with ice
1.2: 0 - 20 °C / |Inert atmosphere
2.1: diethylamino-sulfur trifluoride / dichloromethane / 96 h / -70 - 20 °C / |Inert atmosphere
3.1: hydrogen; palladium 10 on activated carbon / methanol / 20 °C
View Scheme
参考文献
Shanghai Yingli Science And Technology Co., Ltd; Shanghai Pharmvally Innovation Institution Of Biomedicine; Shanghai Chempartner Co., Ltd; XU, Zusheng; QIAN, Su
Patent: EP2676965 A1, 2013 ;
参考文献
Cheymol et al.
Bulletin de la Societe Chimique de France, 1959 , p. 1184
反应条件
potassium hydroxide
T=180°C;
参考文献
Cheymol et al.
Bulletin de la Societe Chimique de France, 1959 , p. 1184
