(S)-(-)-1-(2-萘基)乙醇合成路线 （共 74 条）
反应条件
palladium dichloro (η-2,5-norbornadiene); oxygen; (-)-sparteine in toluene T=80°C; 112 h;
参考文献
Shiigi, Hirofumi; Mori, Hiroyuki; Tanaka, Tomoaki; Demizu, Yosuke; Onomura, Osamu
Tetrahedron Letters, 2008 , vol. 49, # 36 p. 5247 - 5251
反应条件
1: With titanium(IV) isopropylate; (Sa)-2'-[(R)-hydroxy(phenyl)methyl]-(1,1'-binaphthalen)-2-ol in diethyl ether; toluene T=0°C; 1 h; Inert atmosphere; 2: With hydrogenchloride in diethyl ether; water; toluene Inert atmosphere; optical yield given as percent eeenantioselective reaction;
参考文献
Fernandez-Mateos, Emilio; MacIa, Beatriz; Yus, Miguel
Tetrahedron Asymmetry, 2012 , vol. 23, # 10 p. 789 - 794
反应条件
1: With boric acid trimethyl ester; dimethylsulfide borane complex; (-)-3-amino-6,6-dimethyl-2-hydroxy-bicyclo[3.1.1]heptane in tetrahydrofuran T=20°C; 2: With methanol in tetrahydrofuran
参考文献
Krzeminski, Marek P.; Wojtczak, Andrzej
Tetrahedron Letters, 2005 , vol. 46, # 48 p. 8299 - 8302
反应条件
(mer-[(S,S)-1,5-dimethyl-2,4-bis(4-phenyl-1,3-oxazolin-2-yl)benzene(1-)]Ru(CO)Cl)2(ZnCl2); hydrogen; sodium methylate in isopropyl alcohol T=40°C; P=22801.5 Torr; 24 h; Inert atmosphereAutoclave; optical yield given as percent eeenantioselective reaction;
参考文献
Ito, Jun-Ichi; Teshima, Tomoki; Nishiyama, Hisao
Chemical Communications, 2012 , vol. 48, # 8 p. 1105 - 1107
反应条件
tricarbonyl(η6-arene)chromium(0) complex derived from (1S,2R)-N,N-dibutylnorephedrine in hexane; toluene T=0°C; 12 h; Yield given. Yields of byproduct given. Title compound not separated from byproducts;
参考文献
Huang, Wei-Sheng; Hu, Qiao-Sheng; Pu, Lin
Journal of Organic Chemistry, 1999 , vol. 64, # 21 p. 7940 - 7956
反应条件
benzo[1,3,2]dioxaborole; [Rh(cod)(S)-(QUINAP)]BF4 in tetrahydrofuran T=25°C; 2 h;
参考文献
Segarra, Anna M.; Guerrero, Ramon; Claver, Carmen; Fernandez, Elena
Chemistry - A European Journal, 2003 , vol. 9, # 1 p. 191 - 200
反应条件
[Ru2(p-PriC6H4Me)2(μ-Cl)Cl]2; N,N'-methyl-(3-dimethylaminopropyl)-amine; 4-chlorophenyl acetate; Chirazyme(R) 1-2 T=80°C; 45 h;
参考文献
Riermeier, Thomas H.; Gross, Peter; Monsees, Axel; Hoff, Manfred; Trauthwein, Harald
Tetrahedron Letters, 2005 , vol. 46, # 19 p. 3403 - 3406
反应条件
(1R,2R)-α,α,α',α'-tetraphenyl-1,2-cyclohexanedimethanol; TiF4 in CH3CN 1) THF, hexane, 0 deg C to RT, 20 min, 2) THF, hexane, 20 min, 3) THF, hexane, -10 deg C, 12 h then warm to RT; Yield givenMultistep reaction. Yields of byproduct given. Title compound not separated from byproducts;
参考文献
Alegre, Sabina; Dieguez, Montserrat; Pmies, Oscar
Tetrahedron Asymmetry, 2011 , vol. 22, # 8 p. 834 - 839
反应条件
1: With succinic acid anhydride; Candida antarctica lipase B in diethyl ether T=20°C; Enzymatic reaction; 2: With sodium hydroxide in water
参考文献
Bouzemi, Nassima; Debbeche, Hanane; Aribi-Zouioueche, Louisa; Fiaud, Jean-Claude
Tetrahedron Letters, 2004 , vol. 45, # 3 p. 627 - 630
反应条件
Candida antarctica lipase B in diethyl ether T=20°C; Enzymatic reaction;
参考文献
Bouzemi, Nassima; Debbeche, Hanane; Aribi-Zouioueche, Louisa; Fiaud, Jean-Claude
Tetrahedron Letters, 2004 , vol. 45, # 3 p. 627 - 630
