(S)-(-)-1-(2-萘基)乙醇合成路线 （共 74 条）
反应条件
titanium(IV) isopropylate; 1-((S)-2-((R)-hydroxy(naphthalen-2-yl)methyl)naphthalen-1-yl)naphthalen-2-ol in toluene T=-40°C; Schlenk technique; enantioselective reaction;
参考文献
Zheng, Long-Sheng; Jiang, Ke-Zhi; Deng, Yuan; Bai, Xing-Feng; Gao, Guang; Gu, Feng-Lei; Xu, Li-Wen
European Journal of Organic Chemistry, 2013 , # 4 p. 748 - 750
反应条件
(1R)-N-oxyl-1-(N-benzylcarbamoyl)-8-azabicyclo[3.2.1]octane; sodium hydrogencarbonate; sodium bromide in dichloromethane; water T=0°C; Electrochemical reaction; optical yield given as percent eeenantioselective reaction;
参考文献
Demizu, Yosuke; Shiigi, Hirofumi; Mori, Hiroyuki; Matsumoto, Kazuya; Onomura, Osamu
Tetrahedron Asymmetry, 2008 , vol. 19, # 23 p. 2659 - 2665
反应条件
H2SiF6 in methanol; acetonitrile 48 h;
参考文献
Nakamura; Linclau; Curran
Journal of the American Chemical Society, 2001 , vol. 123, # 41 p. 10119 - 10120
反应条件
1: With bis(acetylacetonate)nickel(II); C41H61O8P in tetrahydrofuran T=5°C; 3 h; Inert atmosphere; 2: With hydrogenchloride; water in tetrahydrofuran Inert atmosphere; optical yield given as percent eeenantioselective reaction;
参考文献
Alegre, Sabina; Dieguez, Montserrat; Pmies, Oscar
Tetrahedron Asymmetry, 2011 , vol. 22, # 8 p. 834 - 839
反应条件
1: With benzo[1,3,2]dioxaborole; rhodium complex 2 in toluene T=20°C; Addition; Hydroboration; 2 h; 2: With sodium hydroxide; water; dihydrogen peroxide in toluene T=20°C; Oxidation; 2 h; Title compound not separated from byproducts;
参考文献
Tsuchiya, Yasunori; Uchimura, Hirofumi; Kobayashi, Kazuki; Nishiyama, Hisao
Synlett, 2004 , # 12 p. 2099 - 2102
反应条件
1: With (Sa)-2'-[(R)-hydroxy(phenyl)methyl]-(1,1'-binaphthalen)-2-ol; titanium (IV) isopropoxide in toluene T=-40°C; 1 h; Inert atmosphere; 2: With hydrogenchloride in water Inert atmosphere; optical yield given as percent eeenantioselective reaction;
参考文献
Fernandez-Mateos, Emilio; MacIa, Beatriz; Yus, Miguel
European Journal of Organic Chemistry, 2012 , # 20 p. 3732 - 3736
反应条件
chiral 2-(3',5'-di-t-butylPh)-2-phosphabicyclo[3.3.0]octane in toluene T=20°C; 0.833333 h; Title compound not separated from byproducts;
参考文献
Crittall, Matthew R.; Rzepa, Henry S.; Carbery, David R.
Organic Letters, 2011 , vol. 13, # 5 p. 1250 - 1253
反应条件
Candida antarctica lipase (CAL) immobilized on BIO-M in di-isopropyl ether T=30°C; 0.5 h; Resolution of racemateMolecular sieve; optical yield given as percent eeenantioselective reaction;
参考文献
Ema, Tadashi; Miyazaki, Yuki; Kozuki, Izumi; Sakai, Takashi; Hashimoto, Hideki; Takada, Jun
Green Chemistry, 2011 , vol. 13, # 11 p. 3187 - 3195
反应条件
potassium tert-butylate; (CyRuCl2)2; (1R,2S)-1-amino-2,3-dihydro-1H-inden-2-ol in isopropyl alcohol; acetone T=25°C; 19 h; Title compound not separated from byproducts.;
参考文献
Faller; Lavoie, Adrien R.
Organic Letters, 2001 , vol. 3, # 23 p. 3703 - 3706
反应条件
3 A molecular sieve; oxygen; (-)-sparteine; [(1,3-(2,6-iPr2C6H3)2-1,3-dihydroimidazol-2-ylidene)PdCl2]2 in 1,2-dichloro-ethane T=65°C; 20 h; Title compound not separated from byproducts.;
参考文献
Jensen, David R.; Sigman, Matthew S.
Organic Letters, 2003 , vol. 5, # 1 p. 63 - 65
