(S)-(-)-1-(2-萘基)乙醇合成路线 （共 74 条）
反应条件
(S)-HBTM; N-ethyl-N,N-diisopropylamine in 1,1-dimethylpropan-1-ol; toluene T=-40°C; 5 h; optical yield given as percent ee;
参考文献
Belmessieri, Dorine; Joannesse, Caroline; Woods, Philip A.; MacGregor, Callum; Jones, Caroline; Campbell, Craig D.; Johnston, Craig P.; Duguet, Nicolas; Concellon, Carmen; Bragg, Ryan A.; Smith, Andrew D.
Organic and Biomolecular Chemistry, 2011 , vol. 9, # 2 p. 559 - 570
反应条件
(2S,3R)-3-isopropyl-2-phenyl-3,4-dihydro-2H-pyrimido[2,1-b]benzothiazole; N-ethyl-N,N-diisopropylamine in chloroform T=20 - 25°C; 18 h; optical yield given as percent eeenantioselective reaction;
参考文献
Belmessieri, Dorine; Joannesse, Caroline; Woods, Philip A.; MacGregor, Callum; Jones, Caroline; Campbell, Craig D.; Johnston, Craig P.; Duguet, Nicolas; Concellon, Carmen; Bragg, Ryan A.; Smith, Andrew D.
Organic and Biomolecular Chemistry, 2011 , vol. 9, # 2 p. 559 - 570
反应条件
iodosylbenzene; iron(III) meso-tetraphenylporhinato chloride in dichloromethane T=0°C; 1 h; Yield given. Yields of byproduct given;
参考文献
Zhang, Rui; Yu, Wing-Yiu; Che, Chi-Ming
Tetrahedron Asymmetry, 2005 , vol. 16, # 21 p. 3520 - 3526
反应条件
1: acetyl chloride With 1,4-diaza-bicyclo[2.2.2]octane; (S)-3,3'-bis-(2,4,6-triisopropylphenyl)-BINOL phosphoric acid in diethyl ether T=20°C; 0.0833333 h; Inert atmosphereResolution of racemate; 2: 1-(S)-(naphthalen-2-yl)ethanol in diethyl ether T=-20°C; 5 h; Resolution of racemateInert atmosphere; optical yield given as percent ee;
参考文献
Mandai, Hiroki; Murota, Kyouta; Mitsudo, Koichi; Suga, Seiji
Organic Letters, 2012 , vol. 14, # 13 p. 3486 - 3489
反应条件
50 U aminoacylase E.C. 3.5.1.14 in hexane Acetylation; 168 h;
参考文献
Bakker; Spruijt; Van Rantwijk; Sheldon
Tetrahedron Asymmetry, 2000 , vol. 11, # 8 p. 1801 - 1808
反应条件
immobilized lipase from Candida antarctica (Novozyme SP 435); 1-n-butyl-3-methylimidazolium bistrifluoromethylsulfonylamide T=60°C; P=82508.3 Torr; 65.5 h;
参考文献
Reetz, Manfred T.; Wiesenhoefer, Wolfgang; Francio, Giancarlo; Leitner, Walter
Advanced Synthesis and Catalysis, 2003 , vol. 345, # 11 p. 1221 - 1228
反应条件
1,3-di[(R)-(+)-α-methylbenzyl]imidazolium tetrafluoroborate; potassium tert-butylate in tetrahydrofuran T=-78°C; 1.5 h; Further byproducts given. Title compound not separated from byproducts;
参考文献
Kano, Taichi; Sasaki, Kouji; Maruoka, Keiji
Organic Letters, 2005 , vol. 7, # 7 p. 1347 - 1349
反应条件
1: Na-Pi buffer / acetone / 48 h / tubers of Helianthus tuberosus presence, pH 5.9 2: 12 mg / Na-Pi buffer / acetone / 48 h / tubers of Helianthus tuberosus presence, pH 5.9; other biologically active material: tubers of Solanum tuberosum cv. Saturna View Scheme
参考文献
Laumen, Kurt; Schneider, Manfred P.
Journal of the Chemical Society, Chemical Communications, 1988 , p. 598 - 600
反应条件
1-methyl-1H-imidazole in tetrahydrofuran T=20°C; 2 h; Inert atmosphereAnhydrous conditions; enantioselective reaction;
参考文献
Leclercq, Loic; Suisse, Isabelle; Agbossou-Niedercorn, Francine
European Journal of Organic Chemistry, 2010 , # 14 p. 2696 - 2700
反应条件
1: methyllithium in diethyl ether; toluene T=-5°C; 1 h; Inert atmosphere; 2: With titanium(IV) isopropylate in diethyl ether; toluene T=-5°C; Inert atmosphere; 3: β-naphthaldehyde in diethyl ether; toluene T=-5°C; 24 h; Inert atmosphere; optical yield given as percent eeenantioselective reaction;
参考文献
Huang, Changwei; Yang, Nianfa; Zhang, Anlin; Yang, Liwen
Polymer (United Kingdom), 2012 , vol. 53, # 16 p. 3514 - 3519
