1: ethyl acetate; aqueous NaHCO3 / unter Kuehlung 2: aqueous methanol.NaOH / Hydrogenolyse des Reaktionsprodukts an Palladium in Eisessig enthaltendem Methanol View Scheme

barium dihydroxide

1.1: tert-butylisonitrile; benzotriazol-1-ol / chloroform / 20 °C / Inert atmosphere 2.1: trifluoroacetic acid / chloroform / 1 h / Inert atmosphere 3.1: tert-butylisonitrile; benzotriazol-1-ol / chloroform / 20 °C / Inert atmosphere 4.1: ammonia / methanol / 24 h / Inert atmosphere 5.1: tri-iso-propylsilane; water; trifluoroacetic acid; phenol / 1.5 h / 20 °C / Inert atmosphere 6.1: sodium dihydrogenphosphate; tris-(2-carboxyethyl)-phosphine hydrochloride / pH 7.2 / Inert atmosphere 6.2: Inert atmosphere 7.1: ammonium hydroxide; acetic acid / water / 6 h / pH 7 View Scheme

in toluene 12 h; Heating;