4-羟基-8-甲氧基喹啉-3-羧酸乙酯合成路线 (共 7 条)
反应条件
in dowtherm A T=250°C;
参考文献
Miknis, Greg; Lyssikatos, Joseph P.; Laird, Ellen; Tarlton, Eugene; Buckmelter, Alexandre J.; Ren, Li; Rast, Bryson; Schlacter, Stephen T.; Wenglowsky, Steven Mark
Patent: US2007/49603 A1, 2007 ;
Location in patent: Page/Page column 66 ;
US 20070049603 A1
反应条件
1: T=120 - 150°C; 2: Heating;
参考文献
Zask; Gu; Albright; Du; Hogan; Levin; Chen; Killar; Sung; DiJoseph; Sharr; Roth; Skala; Jin; Cowling; Mohler; Barone; Black; March; Skotnicki
Bioorganic and Medicinal Chemistry Letters, 2003 , vol. 13, # 8 p. 1487 - 1490
反应条件
ethanol; hydrazine hydrate
参考文献
Popli; Dhar
Journal of Scientific and Industrial Research, 1955 , vol. 14 B, p. 261
反应条件
1: aqueous NaOH 2: diphenyl ether / Erhitzen auf Siedetemperatur 3: phosphoryl chloride; phosphorus (V)-chloride View Scheme
参考文献
Lauer et al.
Journal of the American Chemical Society, 1946 , vol. 68, p. 1268
反应条件
1: With trichlorophosphate 2 h; Heating / reflux; 2: With ammonia in water
参考文献
Miknis, Greg; Lyssikatos, Joseph P.; Laird, Ellen; Tarlton, Eugene; Buckmelter, Alexandre J.; Ren, Li; Rast, Bryson; Schlacter, Stephen T.; Wenglowsky, Steven Mark
Patent: US2007/49603 A1, 2007 ;
Location in patent: Page/Page column 66 ;
US 20070049603 A1
反应条件
1: aqueous NaOH 2: diphenyl ether / Erhitzen auf Siedetemperatur View Scheme
参考文献
Lauer et al.
Journal of the American Chemical Society, 1946 , vol. 68, p. 1268
参考文献
Lauer et al.
Journal of the American Chemical Society, 1946 , vol. 68, p. 1268