无水硫酸铜合成路线

参考文献

CEPHALON, INC.; BRESLIN, Henry J.; CURRY, Matthew A.; GINGRICH, Diane E.; LEARN, Keith S.; OTT, Gregory R.; WAGNER, Jason C.
Patent: WO2013/116291 A1, 2013 ;
Location in patent: Page/Page column 207; 208 ;

98-97-52-甲酸吡嗪

2758-98-7无水硫酸铜

参考文献

Hu, Lain-Yen; Ryder, Todd R.; Nikam, Sham S.; Millerman, Elizabeth; Szoke, Balazs G.; Rafferty, Michael F.
Bioorganic and Medicinal Chemistry Letters, 1999 , vol. 9, # 8 p. 1121 - 1126

186581-53-3重氮甲烷+

2762-32-5哌嗪-2-甲酸

2758-98-7无水硫酸铜

参考文献

Hu, Lain-Yen; Ryder, Todd R.; Nikam, Sham S.; Millerman, Elizabeth; Szoke, Balazs G.; Rafferty, Michael F.
Bioorganic and Medicinal Chemistry Letters, 1999 , vol. 9, # 8 p. 1121 - 1126

58632-95-42-(叔丁氧羰基氧亚氨基)-2-苯乙腈+

2758-98-7无水硫酸铜

129799-08-2(+/-)-4-N-Boc-2-哌嗪甲酸甲酯

参考文献

Hu, Lain-Yen; Ryder, Todd R.; Nikam, Sham S.; Millerman, Elizabeth; Szoke, Balazs G.; Rafferty, Michael F.
Bioorganic and Medicinal Chemistry Letters, 1999 , vol. 9, # 8 p. 1121 - 1126

2758-98-7无水硫酸铜+

501-53-1氯甲酸苄酯

129799-11-7N-4-Cbz-哌嗪-2-甲酸甲酯

参考文献

Abbott Laboratories
Patent: US2004/116518 A1, 2004 ;
Location in patent: Page 42 ;

24424-99-5二碳酸二叔丁酯+

2758-98-7无水硫酸铜+

144-55-8碳酸氢钠

171504-98-61,4-二-Boc-哌嗪-2-羧酸甲酯

参考文献

Microcide Pharmaceuticals, Inc.
Patent: US6399629 B1, 2002 ;