2-氯-10-(3-氯丙基)-10H-吩噻嗪合成路线 （共 14 条）
反应条件
sodium hydride in tetrahydrofuran; dimethyl sulfoxide T=20°C;
参考文献
Kalkanidis, Martha; Klonis, Nectarios; Tilley, Leann; Deady, Leslie W
Biochemical Pharmacology, 2002 , vol. 63, # 5 p. 833 - 842
反应条件
ammonia; sodium amide
参考文献
Zhuravlev,S.V. et al.
J. Gen. Chem. USSR (Engl. Transl.), 1962 , vol. 32, p. 1912 - 1914,1889 - 1891
反应条件
sodium hydroxide; tetra(n-butyl)ammonium hydrogensulfate in various solvent(s) 19 h; Ambient temperature;
参考文献
Gozlan; Ladkani; Halpern; et al.
Journal of Heterocyclic Chemistry, 1984 , vol. 21, # 2 p. 613 - 614
反应条件
methanol; 1-chloroethyl chlorocarbonate 1) 1,2-dichloroethane; Yield given. Multistep reaction;
参考文献
Olofson, R. A.; Abbott, Duain E.
Journal of Organic Chemistry, 1984 , vol. 49, # 15 p. 2795 - 2799
反应条件
n-butyllithium; diethyl ether
参考文献
Soc. Usines Chim. Rhone-Poulenc
Patent: US2645640 , 1951 ;
参考文献
Zhuravlev,S.V. et al.
J. Gen. Chem. USSR (Engl. Transl.), 1962 , vol. 32, p. 1912 - 1914,1889 - 1891
反应条件
N,N-dimethyl-formamide
参考文献
Soc. Usines Chim. Rhone-Poulenc
Patent: DE1012915 , 1957 ;
参考文献
Soc. Usines Chim. Rhone-Poulenc
Patent: DE1012915 , 1957 ;
反应条件
1: NaI; butanone 2: K2CO3; toluene View Scheme
参考文献
Cusic,J.W.
Patent: US2766235 , 1956 ;
参考文献
Schering Corp.
Patent: US2860138 , 1956 ;
