1,3-苯并噻唑-2-甲酰肼3-氧化物合成路线 （共 12 条）
反应条件
1: (i) aq. HCl, aq. NaNO2, (ii) /BRN= 1718733/, (reflux) 2: aq. HCl 3: 2-methyl-propan-2-ol View Scheme
参考文献
Takahashi,S. et al.
Chemical and Pharmaceutical Bulletin, 1970 , vol. 18, p. 1176 - 1184
反应条件
1: (i) aq. HCl, aq. NaNO2, (ii) /BRN= 1718733/, (reflux) 2: NH3 / ethanol View Scheme
参考文献
Takahashi,S. et al.
Chemical and Pharmaceutical Bulletin, 1970 , vol. 18, p. 1176 - 1184
反应条件
1: (i) aq. HCl, aq. NaNO2, (ii) /BRN= 1718733/, (reflux) 2: aq. HCl View Scheme
参考文献
Takahashi,S. et al.
Chemical and Pharmaceutical Bulletin, 1970 , vol. 18, p. 1176 - 1184
反应条件
hydrazine hydrate in ethanol
Heating;
参考文献
Takahashi,S. et al.
Chemical and Pharmaceutical Bulletin, 1970 , vol. 18, p. 1176 - 1184
反应条件
1: acetic acid
2: Et3N / acetone / Heating
3: NaOH / Ambient temperature
4: aq. HCl
5: N2H4*H2O / ethanol / Heating
View Scheme
参考文献
Takahashi,S. et al.
Chemical and Pharmaceutical Bulletin, 1970 , vol. 18, p. 1176 - 1184
反应条件
1: Et3N / acetone / Heating
2: NaOH / Ambient temperature
3: aq. HCl
4: N2H4*H2O / ethanol / Heating
View Scheme
参考文献
Takahashi,S. et al.
Chemical and Pharmaceutical Bulletin, 1970 , vol. 18, p. 1176 - 1184
反应条件
1: NaNH2, isopentyl nitrite / liquid ammonia
2: acetic acid
3: Et3N / acetone / Heating
4: NaOH / Ambient temperature
5: aq. HCl
6: N2H4*H2O / ethanol / Heating
View Scheme
参考文献
Takahashi,S. et al.
Chemical and Pharmaceutical Bulletin, 1970 , vol. 18, p. 1176 - 1184
反应条件
1: NaOH / Ambient temperature
2: aq. HCl
3: N2H4*H2O / ethanol / Heating
View Scheme
参考文献
Takahashi,S. et al.
Chemical and Pharmaceutical Bulletin, 1970 , vol. 18, p. 1176 - 1184
反应条件
1: aq. HCl
2: N2H4*H2O / ethanol / Heating
View Scheme
参考文献
Takahashi,S. et al.
Chemical and Pharmaceutical Bulletin, 1970 , vol. 18, p. 1176 - 1184
反应条件
1: (i) aq. HCl, aq. NaNO2, (ii) /BRN= 1718733/, (reflux)
2: aq. HCl
3: CH2Cl2 / Heating
View Scheme
参考文献
Takahashi,S. et al.
Chemical and Pharmaceutical Bulletin, 1970 , vol. 18, p. 1176 - 1184
