4-甲氧基-1H-喹啉-2-酮合成路线 （共 21 条）
反应条件
1: 4-hydroxyquinolin-2(1H)-one With potassium carbonate in N,N-dimethyl-formamide T=90°C; 2 h; 2: CH3X, X=halide in N,N-dimethyl-formamide T=50 - 90°C;
参考文献
Guo, Li-Jun; Wei, Cheng-Xi; Jia, Jing-Hao; Zhao, Li-Ming; Quan, Zhe-Shan
European Journal of Medicinal Chemistry, 2009 , vol. 44, # 3 p. 954 - 958
反应条件
1: 48 percent / POCl3 / 5 h / Heating 2: 70 percent / NaOMe / 24 h / Heating 3: 54 percent / aq. HBr / tetrahydrofuran / 3 h / Heating View Scheme
参考文献
Ramasamy; Balasubramaniam; Mohan
Asian Journal of Chemistry, 2012 , vol. 24, # 10 p. 4726 - 4728
反应条件
in xylene 48 h; Heating;
参考文献
Nickisch, Klaus; Klose, Walter; Nordhoff, Erhard; Bohlmann, Ferdinand
Chemische Berichte, 1980 , vol. 113, # 9 p. 3086 - 3088
反应条件
1: CHCl3 / 12 h / Heating 2: aq. sodium hydroxide 3: 5 h / 180 - 200 °C View Scheme
参考文献
Desai, Vidya G.; Shet, Jyoti B.; Tilve, Santosh G.; Mali, Raghao S.
Journal of Chemical Research - Part S, 2003 , # 10 p. 628 - 629
反应条件
1: CHCl3 / 12 h / Heating 2: aq. sodium hydroxide 3: 5 h / 180 - 200 °C View Scheme
参考文献
Desai, Vidya G.; Shet, Jyoti B.; Tilve, Santosh G.; Mali, Raghao S.
Journal of Chemical Research - Part S, 2003 , # 10 p. 628 - 629
反应条件
T=180 - 200°C; intramolecular Wittig reaction; 5 h;
参考文献
Desai, Vidya G.; Shet, Jyoti B.; Tilve, Santosh G.; Mali, Raghao S.
Journal of Chemical Research - Part S, 2003 , # 10 p. 628 - 629
反应条件
1: 95 percent / methanol / 1.5 h / Ambient temperature; Irradiation 2: 12 percent / tert-BuOK / tetrahydrofuran / 3 h / Ambient temperature View Scheme
参考文献
Sato, Masayuki; Kawakami, Katsuhiro; Kaneko, Chikara
Chemical & Pharmaceutical Bulletin, 1987 , vol. 35, # 3 p. 1319 - 1321
反应条件
1: 95 percent / methanol / 1.5 h / Ambient temperature; Irradiation 2: 65 percent / tert-BuOK / tetrahydrofuran / 3 h / Ambient temperature 3: hydrogen chloride / CH2Cl2 / Ambient temperature 4: 75 percent / potassium carbonate / acetone / 3 h / Heating View Scheme
参考文献
Sato, Masayuki; Kawakami, Katsuhiro; Kaneko, Chikara
Chemical & Pharmaceutical Bulletin, 1987 , vol. 35, # 3 p. 1319 - 1321
反应条件
potassium hydroxide in acetone 14 h; Heating;
参考文献
Reisch, Johannes; Mester, Iuliu
Archiv der Pharmazie (Weinheim, Germany), 1980 , vol. 313, # 9 p. 751 - 755
反应条件
potassium hydroxide in acetone 14 h; Heating;
参考文献
Reisch, Johannes; Mester, Iuliu
Archiv der Pharmazie (Weinheim, Germany), 1980 , vol. 313, # 9 p. 751 - 755
