(2R,3R,5S)-3,5-二甲基-1-苄氧基-2-羟基-8-(4-甲氧基苯氧基)-4-辛酮合成路线 （共 2 条）
反应条件
With acetic acid; tetramethylammonium triacetoxyborohydride in acetonitrile T=-45 - -25°C; Reduction; 72.25 h;
参考文献
Enders, Dieter; Geibel, Gunter; Osborne, Simon Chemistry - A European Journal, 2000 , vol. 6, # 8 p. 1302 - 1309
反应条件
Multi-step reaction with 4 steps 1.1: 83 percent / NaI / acetone / 120 h / Heating2.1: LDA / diethyl ether; hexane / 5 h / 0 °C2.2: 80 percent / diethyl ether; hexane / -100 - 20 °C3.1: 87 percent / MMPP / methanol / -15 °C / pH 74.1: TiCl4; DIPEA / CH2Cl2 / 1.5 h / -78 °C4.2: 64 percent / CH2Cl2 / 2 h / -78 °C
参考文献
Enders, Dieter; Geibel, Gunter; Osborne, Simon Chemistry - A European Journal, 2000 , vol. 6, # 8 p. 1302 - 1309
