4-甲基苯-1,3-二磺酰氯合成路线 （共 5 条）
反应条件
chlorosulfonic acid
T=140 - 150°C;
参考文献
Herzog
Angewandte Chemie, 1926 , vol. 39, p. 729
Full Text Show Details
Pollak et al.
Monatshefte fuer Chemie, 1930 , vol. 55, p. 358,373
反应条件
chlorosulfonic acid
T=145°C; 0.5 h; regioselective reaction;
参考文献
Makrecka, Marina; Zalubovskis, Raivis; Vavers, Edijs; Ivanova, Jekaterina; Grandane, Aiga; Dambrova, Maija
Letters in Drug Design and Discovery, 2013 , vol. 10, # 5 p. 410 - 414
反应条件
sulfuric acid
T=150°C;
参考文献
Deutsche Hydrierwerke
Patent: DE757503 , 1940 ;
DRP/DRBP Org.Chem.
参考文献
Spryskow; Jakowlewa
Zhurnal Obshchei Khimii, 1955 , vol. 25, p. 783,784;engl.Ausg.S.749
反应条件
ammonium hydroxide in water
2 h; Reflux;
参考文献
Makrecka, Marina; Zalubovskis, Raivis; Vavers, Edijs; Ivanova, Jekaterina; Grandane, Aiga; Dambrova, Maija
Letters in Drug Design and Discovery, 2013 , vol. 10, # 5 p. 410 - 414
