2,6-二氯-3-硝基苯磺酸合成路线 (共 4 条)
反应条件
nitric acid in methanol; sulfuric acid
参考文献
SmithKline Beecham Corporation
Patent: US6500863 B1, 2002 ;
US 6500863 B1
反应条件
1: LiOH / methanol
2: H2SO4; HNO3
View Scheme
参考文献
McCleland, Brent W.; Davis, Roderick S.; Palovich, Michael R.; Widdowson, Katherine L.; Werner, Michelle L.; Burman, Miriam; Foley, James J.; Schmidt, Dulcie B.; Sarau, Henry M.; Rogers, Martin; Salyers, Kevin L.; Gorycki, Peter D.; Roethke, Theresa J.; Stelman, Gary J.; Azzarano, Leonard M.; Ward, Keith W.; Busch-Petersen, Jakob
Bioorganic and Medicinal Chemistry Letters, 2007 , vol. 17, # 6 p. 1713 - 1717
反应条件
sulfuric acid; nitric acid
参考文献
McCleland, Brent W.; Davis, Roderick S.; Palovich, Michael R.; Widdowson, Katherine L.; Werner, Michelle L.; Burman, Miriam; Foley, James J.; Schmidt, Dulcie B.; Sarau, Henry M.; Rogers, Martin; Salyers, Kevin L.; Gorycki, Peter D.; Roethke, Theresa J.; Stelman, Gary J.; Azzarano, Leonard M.; Ward, Keith W.; Busch-Petersen, Jakob
Bioorganic and Medicinal Chemistry Letters, 2007 , vol. 17, # 6 p. 1713 - 1717
反应条件
1: With potassium hydroxide
2: With phosphorus pentachloride; trichlorophosphate
参考文献
McCleland, Brent W.; Davis, Roderick S.; Palovich, Michael R.; Widdowson, Katherine L.; Werner, Michelle L.; Burman, Miriam; Foley, James J.; Schmidt, Dulcie B.; Sarau, Henry M.; Rogers, Martin; Salyers, Kevin L.; Gorycki, Peter D.; Roethke, Theresa J.; Stelman, Gary J.; Azzarano, Leonard M.; Ward, Keith W.; Busch-Petersen, Jakob
Bioorganic and Medicinal Chemistry Letters, 2007 , vol. 17, # 6 p. 1713 - 1717