(R)-(+)-3-羟基-3-苯丙酸合成路线 (共 59 条)
反应条件
peracetic acid; disodium hydrogenphosphate in dichloromethane T=25°C;
参考文献
Evans,D.A.; Nelson,J.V.; Vogel,E.
Journal of the American Chemical Society, 1981 , vol. 103, p. 3099
反应条件
sodium hydroxide; silver nitrate
参考文献
Kitanosono, Taku; Xu, Pengyu; Kobayashi, Shu
Chemistry - An Asian Journal, 2014 , vol. 9, # 1 p. 179 - 188
反应条件
sodium hydroxide in methanol; water 0.5 h; Ambient temperature;
参考文献
Ishihara, Kazuaki; Maruyama, Tohru; Mouri, Makoto; Gao, Qingzhi; Furuta,Kyoji; Yamamoto, Hisashi
Bulletin of the Chemical Society of Japan, 1993 , vol. 66, # 11 p. 3483 - 3491
反应条件
sodium periodate in methanol; water Oxidation;
参考文献
Palomo, Claudio; Oiarbide, Mikel; Aizpurua, Jesus M.; Gonzalez, Alberto; Garcia, Jesus M.; Landa, Cristina; Odriozola, Ibon; Linden, Anthony
Journal of Organic Chemistry, 1999 , vol. 64, # 22 p. 8193 - 8200
反应条件
1: With ozone in dichloromethane T=-78°C; Oxidation; 2: With dihydrogen peroxide Oxidation; Further stages.;
参考文献
Marquez, Francesc; Llebaria, Amadeu; Delgado, Antonio
Organic Letters, 2000 , vol. 2, # 4 p. 547 - 549
反应条件
potassium hydroxide in methanol; water 15 h; Heating;
参考文献
Devant, Ralf; Braun, Manfred
Chemische Berichte, 1986 , vol. 119, # 7 p. 2191 - 2207
反应条件
sodium periodate in methanol
参考文献
Palomo, Claudio; Gonzalez, Alberto; Garcia, Jesus M.; Landa, Cristina; Oiarbide, Mikel; Rodriguez, Santiago; Linden, Anthony
Angewandte Chemie - International Edition, 1998 , vol. 37, # 1-2 p. 180 - 182
反应条件
(Ipc)2BH in tetrahydrofuran T=20°C; 55 h; Title compound not separated from byproducts.;
参考文献
Veeraraghavan Ramachandran; Brown, Herbert C.; Pitre, Sangeeta
Organic Letters, 2001 , vol. 3, # 1 p. 17 - 18
反应条件
1: 99 percent / H2 / 5percent Pd-C / aq. ethanol / 14 h / 2327.2 Torr 2: NEt3 / CH2Cl2 3: lipase PS-30 from Pseudomonas sp., phosphate buffer pH 7 View Scheme
参考文献
Boaz, Neil W.
Journal of Organic Chemistry, 1992 , vol. 57, # 15 p. 4289 - 4292
反应条件
lithium hydroxide hydrate; water in acetonitrile 2 h;
参考文献
Khatik, Gopal L.; Khurana, Ravi; Kumar, Varun; Nair, Vipin A.
Synthesis, 2011 , # 19 art. no. Z54411SS, p. 3123 - 3132