2-氧代-2,3-二氢苯并恶唑-6-磺酰氯合成路线 （共 4 条）
反应条件
chlorosulfonic acid T=5 - 60°C; 2 h;
参考文献
Karimova; Dushamov; Kuryazov; Mukhamedov
Chemistry of Heterocyclic Compounds, 2011 , vol. 47, # 1 p. 90 - 95
反应条件
chlorosulfonic acid; thionyl chloride
参考文献
Hoechst Aktiengesellschaft
Patent: US5136043 A1, 1992 ;
参考文献
Scudi; Buhs
Journal of the American Chemical Society, 1941 , vol. 63, p. 879
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Am. Cyanamid Co.
Patent: US2333445 , 1941 ;
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Thorpe; Williams
Biochemical Journal, 1941 , vol. 35, p. 61,64
反应条件
1: benzoxazolone-6-sulphonyl chloride With sodium hydrogencarbonate; sodium sulfite in water
T=75°C; 1 h;
2: chloroacetic acid in water
48 h; Heating;
参考文献
Park, Chang Ha; Siomboing, Xavier; Yous, Said; Gressier, Bernard; Luyckx, Michel; Chavatte, Philippe
European Journal of Medicinal Chemistry, 2002 , vol. 37, # 6 p. 461 - 468
