4-[乙基(7-均三甲苯基-2,5,6-三甲基-7H-吡咯并[2,3-d]嘧啶-4-基)氨基]-1-丁醇盐酸盐(1:1)合成路线 （共 3 条）
反应条件
hydrogen; palladium on activated charcoal in ethanol T=20°C; 12 h;
参考文献
Hiebel, Anne-Cecile; Partilla, John S.; Rothman, Richard B.; Jacobson, Arthur E.; Rice, Kenner C.
Journal of Labelled Compounds and Radiopharmaceuticals, 2006 , vol. 49, # 7 p. 635 - 640
反应条件
1: 98 percent / LiAlH4 / tetrahydrofuran / 3 h / Heating 2: dimethylsulfoxide / 6 h / 130 °C View Scheme
参考文献
Hsin, Ling-Wei; Webster, Elizabeth L.; Chrousos, George P.; Gold, Philip W.; Eckelman, William C.; Contoreggi, Carlo; Rice, Kenner C.
Bioorganic and Medicinal Chemistry Letters, 2000 , vol. 10, # 8 p. 707 - 710
反应条件
in dimethyl sulfoxide T=130°C; Substitution; 5 h;
参考文献
Hsin, Ling-Wei; Tian, Xinrong; Webster, Elizabeth L.; Coop, Andrew; Caldwell, Timothy M.; Jacobson, Arthur E.; Chrousos, George P.; Gold, Philip W.; Habib, Kamal E.; Ayala, Alejandro; Eckelman, William C.; Contoreggi, Carlo; Rice, Kenner C.
Bioorganic and Medicinal Chemistry, 2002 , vol. 10, # 1 p. 175 - 183
