2-(吡啶-2-羰基)苯甲酸合成路线 (共 4 条)
反应条件
in nitrobenzene 1.) 100 deg C, 2.) 3 h, 160-165 deg C;
参考文献
Karlivan, G. A.; Valter, R. E.
Journal of Organic Chemistry USSR (English Translation), 1984 , vol. 20, p. 605 - 606
Zhurnal Organicheskoi Khimii, 1984 , vol. 20, p. 665 - 666
反应条件
1: 2-Bromobenzoic acid With n-butyllithium in tetrahydrofuran T=-78°C; 0.5 h; 2: 2-pyridyl carboxylic ester in tetrahydrofuran T=-78°C;
参考文献
Lim, Chae Jo; Lee, Ka Eun; Lee, Byung Ho; Oh, Kwang-Seok; Yi, Kyu Yang
Bulletin of the Korean Chemical Society, 2012 , vol. 33, # 7 p. 2389 - 2392
反应条件
n-butyllithium 1.) ether, hexane, -78 deg C, 30 min, 2.) THF, ether, hexane, -78 deg C, 1 h; Yield given. Multistep reaction;
参考文献
Yamaguchi; Kamei; Koga; Akima; Kuroki; Ohi
Journal of Medicinal Chemistry, 1993 , vol. 36, # 25 p. 4052 - 4060
反应条件
2,2,6,6-tetramethylpiperidinyl-lithium in tetrahydrofuran; hexane
T=0°C; 2 h;
参考文献
Rebstock, Anne-Sophie; Mongin, Florence; Trecourt, Francois; Queguiner, Guy
Organic and Biomolecular Chemistry, 2004 , vol. 2, # 3 p. 291 - 295