2-(3-硝基苯胺基)苯甲酸合成路线 （共 20 条）
反应条件
pyridine; copper; potassium carbonate in water 1 h; Heating;
参考文献
Pellon, Rolando F.; Mamposo, Taimirys; Carrasco, Ramon; Rodes, Lorenzo
Synthetic Communications, 1996 , vol. 26, # 20 p. 3877 - 3883
反应条件
1: With potassium hydroxide in ethanol; water T=20 - 100°C; Inert atmosphere; 2: With hydrogenchloride in water T=0°C; pH=2; Inert atmosphere;
参考文献
Adeniji, Adegoke O.; Twenter, Barry M.; Byrns, Michael C.; Jin, Yi; Chen, Mo; Winkler, Jeffrey D.; Penning, Trevor M.
Journal of Medicinal Chemistry, 2012 , vol. 55, # 5 p. 2311 - 2323
反应条件
n-ethyl morpholine; copper diacetate in N,N-dimethyl-formamide T=145°C; 3 h;
参考文献
Kaltenbronn; Scherrer; Short; Jones; Beatty; Saka; Winder; Wax; Williamson
Arzneimittel-Forschung/Drug Research, 1983 , vol. 33, # 4 A p. 621 - 627
反应条件
sodium acetate; anhydrous copper acetate in water 6 h; Heating;
参考文献
Girisha, Hanakere R.; Srinivasa, Gejjalagere R.; Gowda, D. Channe
Journal of Chemical Research, 2006 , # 5 p. 342 - 344
反应条件
1.1: palladium diacetate; caesium carbonate; 2,2'-bis-(diphenylphosphino)-1,1'- binaphthyl / toluene / 20 - 120 °C / Inert atmosphere 2.1: potassium hydroxide / ethanol; water / 20 - 100 °C / Inert atmosphere 2.2: 0 °C / pH 2 / Inert atmosphere View Scheme
参考文献
Adeniji, Adegoke O.; Twenter, Barry M.; Byrns, Michael C.; Jin, Yi; Chen, Mo; Winkler, Jeffrey D.; Penning, Trevor M.
Journal of Medicinal Chemistry, 2012 , vol. 55, # 5 p. 2311 - 2323
反应条件
3-methyl-1-butanol; copper
参考文献
Ullmann; Bader
Justus Liebigs Annalen der Chemie, 1907 , vol. 355, p. 330
反应条件
1: 1.) POCl3 / 2.) 20 deg C, 10 min 2: 78 percent / POCl3 / 2 h / 120 °C 3: 1.) phenol / 1.) 100 deg C, 15 min, 2.) 70-75 deg C, 30 min View Scheme
参考文献
Denny, William A.; Atwell, Graham J.; Anderson, Robert F.; Wilson, William R.
Journal of Medicinal Chemistry, 1990 , vol. 33, # 5 p. 1288 - 1295
反应条件
trichlorophosphate 2.) 20 deg C, 10 min; Yield given. Multistep reaction;
参考文献
Denny, William A.; Atwell, Graham J.; Anderson, Robert F.; Wilson, William R.
Journal of Medicinal Chemistry, 1990 , vol. 33, # 5 p. 1288 - 1295
反应条件
1: POCl3 2: 0.33 h / 60 °C View Scheme
参考文献
Acheson, R. Morrin; Constable, Edwin C.; Wright, R. Gordon McR.; Taylor, Grahame M.
Journal of Chemical Research, Miniprint, 1983 , # 1 p. 101 - 132
反应条件
1: 1.) POCl3 / 2.) 20 deg C, 10 min 2: 78 percent / POCl3 / 2 h / 120 °C 3: 1.) phenol / 1.) 100 deg C, 15 min, 2.) 70-75 deg C, 30 min View Scheme
参考文献
Denny, William A.; Atwell, Graham J.; Anderson, Robert F.; Wilson, William R.
Journal of Medicinal Chemistry, 1990 , vol. 33, # 5 p. 1288 - 1295
