反应条件
Multi-step reaction with 2 steps 1.1: n-BuLi / tetrahydrofuran; hexane / 1.5 h / -78 °C1.2: 85 percent / tetrahydrofuran; hexane / -78 - 20 °C2.1: 88 percent / 6N aq. HCl / 1,2-dimethoxy-ethane / 1.5 h / Heating
参考文献
Corbett, Jeffrey W.; Ko, Soo S.; Rodgers, James D.; Gearhart, Lisa A.; Magnus, Nicholas A.; Bacheler, Lee T.; Diamond, Sharon; Jeffrey, Susan; Klabe, Ronald M.; Cordova, Beverly C.; Garber, Sena; Logue, Kelly; Trainor, George L.; Anderson, Paul S.; Erickson-Viitanen, Susan K. Journal of Medicinal Chemistry, 2000 , vol. 43, # 10 p. 2019 - 2030