2-氯-3-(羟基甲基)苯酚合成路线 （共 5 条）
反应条件
methanol; sodium tetrahydroborate T=0°C; 0.5 h;
参考文献
MERCK SHARP and DOHME CORP.; PIO, Barbara; PASTERNAK, Alexander; SHAHRIPOUR, Aurash; TANG, Haifeng; WALSH, Shawn
Patent: WO2013/90271 A1, 2013 ;
Location in patent: Page/Page column 44 ;
反应条件
borane in tetrahydrofuran T=0 - 60°C;
参考文献
Syntex (U.S.A.) LLC
Patent: US6335/459 B1, 2002 ;
Location in patent: Example 1 ;
Title/Abstract Full Text Show Details
Syntex (U.S.A.) LLC
Patent: US6335459 B1, 2002 ;
Location in patent: Example 1 ;
US 6335459 B1
参考文献
Lock
Monatshefte fuer Chemie, 1930 , vol. 55, p. 307,311
反应条件
1: glacial acetic acid; chlorine 2: concentrated aqueous KOH / 60 - 70 °C View Scheme
参考文献
Lock
Monatshefte fuer Chemie, 1930 , vol. 55, p. 307,311
反应条件
potassium hydroxide
T=100°C;
参考文献
Lock
Monatshefte fuer Chemie, 1930 , vol. 55, p. 307,311
