4-氯-1H-吡咯-2-羧酸合成路线 （共 2 条）
反应条件
1: With sodium hydroxide in tetrahydrofuran; water T=20°C; 1 h; 2: With hydrogenchloride in water pH=5;
参考文献
ADDEX PHARMACEUTICALS SA
Patent: WO2006/123257 A2, 2006 ;
Location in patent: Page/Page column 58 ;
WO 2006/123257 A2
反应条件
1: With sulfuryl dichloride in chloroform T=20°C; Cooling with ice; 2: With water; sodium hydroxide T=20°C; 0.5 h;
参考文献
Clark, Benjamin R.; O'Connor, Stephen; Fox, Deirdre; Leroy, Jacques; Murphy, Cormac D.
Organic and Biomolecular Chemistry, 2011 , vol. 9, # 18 p. 6306 - 6311
