4-羟基-1H-吲哚-2-甲酸甲酯合成路线 （共 2 条）
反应条件
1: With boron tribromide in dichloromethane T=0°C; 2 h; 2: With water; sodium hydrogencarbonate in dichloromethane pH=7;
参考文献
NOVARTIS AG; NOVARTIS PHARMA GmbH
Patent: WO2005/77932 A2, 2005 ;
Location in patent: Page/Page column 60 ;
WO 2005/077932 A2
反应条件
1: 1.) K2CO3 / 1.) Me2CO, heating; 2.) MeOH 2: 33 percent / xylene / Heating 3: H2 / Pd-C / methanol View Scheme
参考文献
Hardy, George W.; Bull, Donald; Jones, Haydn T.; Mills, Gail; Allan, Geoffrey
Tetrahedron Letters, 1988 , vol. 29, # 7 p. 799 - 802
