4,5,6,7-四氢-1,2-苯并恶唑-3-醇合成路线 （共 3 条）
反应条件
1: With sodium hydroxide; hydroxylamine hydrochloride in methanol; water T=-70 - 0°C; 2 h; 2: With hydrogenchloride in methanol; water; acetone Reflux;
参考文献
Clausen, Rasmus P.; Naur, Peter; Kristensen, Anders S.; Greenwood, Jeremy R.; Strange, Mette; Brauner-Osborne, Hans; Jensen, Anders A.; Nielsen, Anne Sophie T.; Geneser, Ulla; Ringgaard, Lone M.; Nielsen, Birgitte; Pickering, Darryl S.; Brehm, Lotte; Gajhede, Michael; Krogsgaard-Larsen, Povl; Kastrup, Jette S.
Journal of Medicinal Chemistry, 2009 , vol. 52, # 15 p. 4911 - 4922
反应条件
hydrogenchloride in methanol
参考文献
Jacquier,R. et al.
Bulletin de la Societe Chimique de France, 1970 , p. 1978 - 1985
反应条件
sodium hydroxide; hydroxylamine hydrochloride T=0 - 5°C; 1 h; Yield given. Yields of byproduct given;
参考文献
Jacobsen; Kolind-Andersen; Christensen
Canadian Journal of Chemistry, 1984 , vol. 62, # 10 p. 1940 - 1944
