5-（4-甲氧基苯基）-2-氯嘧啶合成路线 （共 7 条）
反应条件
potassium fluoride; palladium diacetate in methanol T=120°C; Suzuki coupling; 0.333333 h; microwave irradiation;
参考文献
Colombo, Matteo; Giglio, Marco; Peretto, Ilaria
Journal of Heterocyclic Chemistry, 2008 , vol. 45, # 4 p. 1077 - 1081
反应条件
tetrakis(triphenylphosphine) palladium(0) in tetrahydrofuran T=80°C; chemoselective reaction;
参考文献
Mosquera, Angeles; Riveiros, Ricardo; Sestelo, Jose Perez; Sarandeses, Luis A.
Organic Letters, 2008 , vol. 10, # 17 p. 3745 - 3748
反应条件
1: TsOH / toluene / 110 °C 2: PCl3; POCl3 / Heating View Scheme
参考文献
Sui, Zhihua; Guan, Jihua; Macielag, Mark J.; Jiang, Weiqin; Qiu, Yuhong; Kraft, Patricia; Bhattacharjee, Sheela; John, T. Matthew; Craig, Elizabeth; Haynes-Johnson, Donna; Clancy, Joanna
Bioorganic and Medicinal Chemistry Letters, 2003 , vol. 13, # 4 p. 761 - 765
反应条件
1: 61 percent / HCl / ethanol / 3 h / Heating 2: phosphoryl chloride; N,N-dimethylaniline / 1 h / Heating View Scheme
参考文献
Allen, David W.; Buckland, David J.; Hutley, Barrie G.
Zeitschrift fuer Naturforschung, Teil B: Anorganische Chemie, Organische Chemie, 1980 , vol. 35, # 4 p. 463 - 467
反应条件
trichlorophosphate; phosphorus trichoride Heating;
参考文献
Sui, Zhihua; Guan, Jihua; Macielag, Mark J.; Jiang, Weiqin; Qiu, Yuhong; Kraft, Patricia; Bhattacharjee, Sheela; John, T. Matthew; Craig, Elizabeth; Haynes-Johnson, Donna; Clancy, Joanna
Bioorganic and Medicinal Chemistry Letters, 2003 , vol. 13, # 4 p. 761 - 765
反应条件
N,N-dimethyl-aniline; trichlorophosphate 1 h; Heating;
参考文献
Allen, David W.; Buckland, David J.; Hutley, Barrie G.
Zeitschrift fuer Naturforschung, Teil B: Anorganische Chemie, Organische Chemie, 1980 , vol. 35, # 4 p. 463 - 467
反应条件
in N,N-dimethyl-formamide
T=120°C; 16 h;
参考文献
Sui, Zhihua; Guan, Jihua; Macielag, Mark J.; Jiang, Weiqin; Zhang, Suying; Qiu, Yuhong; Kraft, Patricia; Bhattacharjee, Sheela; John, T. Matthew; Haynes-Johnson, Donna; Clancy, Joanna
Journal of Medicinal Chemistry, 2002 , vol. 45, # 19 p. 4094 - 4096
