beta-D-5-脱氧呋喃木糖三乙酸酯合成路线 （共 28 条）
反应条件
1.1: 88 percent / SnCl2*2H2O; conc. H2SO4 / 20 h / 40 - 45 °C 2.1: 50 percent / pyridine / CH2Cl2 / 4 h / 0 °C 3.1: 95 percent / Li(tBuO)3AlH / tetrahydrofuran / 1 h / 0 °C 4.1: H2SO4 (0.04N) / 3 h / 80 - 90 °C 4.2: pyridine / 16 h / 20 °C View Scheme
参考文献
Sairam, Pothukuchi; Puranik, Ramachandra; Sreenivasa Rao, Bhatraju; Veerabhadra Swamy, Ponnapalli; Chandra, Sharad
Carbohydrate Research, 2003 , vol. 338, # 4 p. 303 - 306
反应条件
1.1: 50 percent / pyridine / CH2Cl2 / 4 h / 0 °C 2.1: 95 percent / Li(tBuO)3AlH / tetrahydrofuran / 1 h / 0 °C 3.1: H2SO4 (0.04N) / 3 h / 80 - 90 °C 3.2: pyridine / 16 h / 20 °C View Scheme
参考文献
Sairam, Pothukuchi; Puranik, Ramachandra; Sreenivasa Rao, Bhatraju; Veerabhadra Swamy, Ponnapalli; Chandra, Sharad
Carbohydrate Research, 2003 , vol. 338, # 4 p. 303 - 306
反应条件
sulfuric acid; acetic acid T=20°C; Acetylation; 2 h; Title compound not separated from byproducts.;
参考文献
Wang, Guangyi; Tam, Robert C.; Gunic, Esmir; Du, Jinfa; Bard, Josie; Pai, Bharati
Journal of Medicinal Chemistry, 2000 , vol. 43, # 13 p. 2566 - 2574
反应条件
1.1: 80 percent / NaBH4 / dimethylsulfoxide / 12 h / 80 - 85 °C 2.1: H2SO4 (0.04N) / 3 h / 80 - 90 °C 2.2: pyridine / 16 h / 20 °C View Scheme
参考文献
Sairam, Pothukuchi; Puranik, Ramachandra; Sreenivasa Rao, Bhatraju; Veerabhadra Swamy, Ponnapalli; Chandra, Sharad
Carbohydrate Research, 2003 , vol. 338, # 4 p. 303 - 306
反应条件
1.1: 89 percent / NaBH4 / dimethylsulfoxide / 2 h / 20 °C 2.1: H2SO4 (0.04N) / 3 h / 80 - 90 °C 2.2: pyridine / 16 h / 20 °C View Scheme
参考文献
Sairam, Pothukuchi; Puranik, Ramachandra; Sreenivasa Rao, Bhatraju; Veerabhadra Swamy, Ponnapalli; Chandra, Sharad
Carbohydrate Research, 2003 , vol. 338, # 4 p. 303 - 306
反应条件
1.1: 95 percent / Li(tBuO)3AlH / tetrahydrofuran / 1 h / 0 °C 2.1: H2SO4 (0.04N) / 3 h / 80 - 90 °C 2.2: pyridine / 16 h / 20 °C View Scheme
参考文献
Sairam, Pothukuchi; Puranik, Ramachandra; Sreenivasa Rao, Bhatraju; Veerabhadra Swamy, Ponnapalli; Chandra, Sharad
Carbohydrate Research, 2003 , vol. 338, # 4 p. 303 - 306
反应条件
1: 5-deoxy-2,3-O-isopropylidene-1-O-methyl-β-D-ribofuranose With sulfuric acid T=80 - 90°C; 3 h; 2: acetic anhydride With pyridine T=20°C; 16 h;
参考文献
Sairam, Pothukuchi; Puranik, Ramachandra; Sreenivasa Rao, Bhatraju; Veerabhadra Swamy, Ponnapalli; Chandra, Sharad
Carbohydrate Research, 2003 , vol. 338, # 4 p. 303 - 306
反应条件
1: 3.83 g / pyridine / 20 °C 2: AcOH; conc. H2SO4 / 2 h / 20 °C View Scheme
参考文献
Wang, Guangyi; Tam, Robert C.; Gunic, Esmir; Du, Jinfa; Bard, Josie; Pai, Bharati
Journal of Medicinal Chemistry, 2000 , vol. 43, # 13 p. 2566 - 2574
反应条件
1: 89 percent / n-Bu3SnH, AIBN / toluene / 3 h / Heating 2: 70percent aq. AcOH / 24 h / 80 - 90 °C 3: pyridine, DMAP View Scheme
参考文献
Pakulski, Z.; Zamojski, A.
Polish Journal of Chemistry, 1995 , vol. 69, # 6 p. 912 - 917
反应条件
1: 70percent aq. AcOH / 24 h / 80 - 90 °C 2: pyridine, DMAP View Scheme
参考文献
Pakulski, Z.; Zamojski, A.
Polish Journal of Chemistry, 1995 , vol. 69, # 6 p. 912 - 917
