1-[2-(羟基甲基)-1-吡咯烷]乙酮合成路线 （共 3 条）
反应条件
1: in ethyl acetate T=20°C; 8 h; Inert atmosphere; 2: With potassium carbonate in ethyl acetate T=20°C; Inert atmosphere; chemoselective reaction;
参考文献
Temperini, Andrea; Terlizzi, Raffaella; Testaferri, Lorenzo; Tiecco, Marcello
Synthetic Communications, 2010 , vol. 40, # 2 p. 295 - 302
反应条件
in dichloromethane T=0°C; 3 h;
参考文献
Bischofberger, Norbert; Waldmann, Herbert; Saito, Tohru; Simon, Ethan S.; Lees, Watson; et al.
Journal of Organic Chemistry, 1988 , vol. 53, # 15 p. 3457 - 3465
反应条件
1: SOCl2 / CHCl3 / 4.5 h / 0 °C 2: NaN3, KI / dimethylformamide / 8 h 3: LiAlH4 / diethyl ether / 8 h View Scheme
参考文献
Bishop; Mathis; Gerdes; Whitney; Eaton; Mailman
Journal of Medicinal Chemistry, 1991 , vol. 34, # 5 p. 1612 - 1624
