2-羟基-3-吡嗪羧酸甲酯合成路线 （共 5 条）
反应条件
thionyl chloride T=20°C;
参考文献
Kim, Myong Jung
Synthetic Communications, 2010 , vol. 40, # 20 p. 2988 - 2999
反应条件
1: 1.) aq. NaNO2, H2SO4 / 1.) 10-16 deg C, 30 min, 2.) reflux, 30 min 2: 64 percent / HCl(gas) / 2.5 h / Heating View Scheme
参考文献
Krapcho, A. Paul; Gallagher, Cynthia E.; Hammach, Abdelhakim; Ellis, Michael; Menta, Ernesto; Oliva, Ambrogio
Journal of Heterocyclic Chemistry, 1997 , vol. 34, # 1 p. 27 - 32
反应条件
hydrogenchloride; sodium azide; sodium acetate; sodium nitrite Yield given. Multistep reaction. Yields of byproduct given;
参考文献
Okawa, Tomohiro; Eguchi, Shoji; Kakehi, Akikazu
Journal of the Chemical Society - Perkin Transactions 1, 1996 , # 3 p. 247 - 254
反应条件
thionyl chloride; N,N-dimethyl-formamide in toluene T=80°C; 3 h;
参考文献
Okawa, Tomohiro; Eguchi, Shoji; Kakehi, Akikazu
Journal of the Chemical Society - Perkin Transactions 1, 1996 , # 3 p. 247 - 254
参考文献
McDonald; Ellingson
Journal of the American Chemical Society, 1947 , vol. 69, p. 1034,1035
Full Text Show Details
Kushner et al.
Journal of the American Chemical Society, 1952 , vol. 74, p. 3617,3618,3620
