(3-甲氧基苯甲酰)乙酸乙酯合成路线 （共 14 条）
反应条件
1: p.toluenesulfonic acid / benzene / Heating
2: Na / various solvent(s) / Heating
3: 70 percent / NaOH / ethanol / Heating
4: 55 percent / neat (no solvent) / Heating
5: 71 percent / sulfur / neat (no solvent) / 0.5 h / 260 °C
View Scheme
参考文献
Winters; Odasso; Conti; et al.
European Journal of Medicinal Chemistry, 1984 , vol. 19, # 3 p. 215 - 218
反应条件
1: p.toluenesulfonic acid / benzene / Heating
2: Na / various solvent(s) / Heating
3: 70 percent / NaOH / ethanol / Heating
4: 55 percent / neat (no solvent) / Heating
View Scheme
参考文献
Winters; Odasso; Conti; et al.
European Journal of Medicinal Chemistry, 1984 , vol. 19, # 3 p. 215 - 218
反应条件
1: 82 percent / p.toluenesulfonic acid / benzene / 4 h / Heating
2: 47 percent / Na / ethanol / 0.5 h / Heating
3: 95 percent / NaOH / methanol / 4 h / Heating
4: 90 percent / neat (no solvent) / 1 h / 260 °C
View Scheme
参考文献
Winters; Odasso; Conti; et al.
European Journal of Medicinal Chemistry, 1984 , vol. 19, # 3 p. 215 - 218
反应条件
1: NH2OH*HCl / ethanol
2: POCl3
View Scheme
参考文献
Nantermet, Philippe G; Barrow, James C.; Lundell, George F.; Pellicore, Janetta M.; Rittle, Kenneth E.; Young, MaryBeth; Freidinger, Roger M.; Connolly, Thomas M.; Condra, Cindra; Karczewski, Jerzy; Bednar, Rodney A.; Gaul, Stanley L.; Gould, Robert J.; Prendergast, Kris; Selnick, Harold G.
Bioorganic and Medicinal Chemistry Letters, 2002 , vol. 12, # 3 p. 319 - 323
